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Human NGFB Protein expressed in CHO Cells - ABIN2003789
Ullrich, Gray, Berman, Dull: Human beta-nerve growth factor gene sequence highly homologous to that of mouse. in Nature 1983
Show all 6 Pubmed References
Mouse (Murine) NGFB Protein expressed in Mouse - ABIN804474
Varon, Raiborn: Dissociation, fractionation and culture of chick embryo sympathetic ganglionic cells. in Journal of neurocytology 1996
Mechanoinsensitive ''silent'' nociceptors are characterized by the expression of the nicotinic acetylcholine receptor subunit alpha (zeige CHRNA1 Proteine)-3 (CHRNA3 (zeige CHRNA3 Proteine)); the mechanically gated ion channel PIEZO2 mediates NGF-induced mechanosensitivity in these neurons.
antibodies raised against NGF, TrkA (zeige NTRK1 Proteine), and p75 (zeige NGFR Proteine) (also known as CD271 (zeige NGFR Proteine)) were used to explore the expression of these antigens in the non-decalcified young mouse femur.
both in vivo mechanical loading and in vitro mechanical stretch were shown to induce the profound up-regulation of NGF in osteoblasts within 1 h of loading.
This study may represent a common mechanism for selective follicular activation induced by a localized increase in NGF in interstitial cells and mediated via the mTOR (zeige FRAP1 Proteine) signaling pathway.
nerve growth factor (NGF) signaling through neurotrophic tyrosine kinase receptor type 1 (TrkA (zeige NTRK1 Proteine)) directs innervation of the developing mouse femur to promote vascularization and osteoprogenitor lineage progression.
These data support a role for islet NGF in fine-tuning insulin (zeige INS Proteine) secretion.
Mechanical stress-induced upregulation of NGF in colon SMC (zeige DYM Proteine) underlies the visceral hypersensitivity in bowel obstruction through increased gene expression and activity of tetrodotoxin-resistant Na channels in sensory neurons.
results suggest that perivascular nerves innervate neovessels as neovasculatures mature and that NGF accelerates the innervation of perivascular nerves in neovessels.
These findings reveal a non-neuronal role for neurotrophins and identify a new regulatory pathway in insulin (zeige INS Proteine) secretion that can be targeted to ameliorate beta cell dysfunction.
NGF signalling directly controls basal APP (zeige APP Proteine) phosphorylation, subcellular localization and BACE (zeige BACE Proteine) cleavage.
The results suggest an interaction between NGF, GDNF and MMP-9 (zeige MMP9 Proteine) during the transition to malignancy in prostate cancer (PC). Also this interaction may involve in regulating PC cell differentiation, tumor invasion, progression, and the agressiveness of PC.
the anti-tumor activity of oleuropein against hepatocellular carcinoma could be attributed to influencing the pro-NGF/NGF balance via affecting MMP-7 (zeige MMP7 Proteine) activity without affecting the gene expression of NGF
co-expression patterns of NGF and heme oxygenase-1 (zeige HMOX1 Proteine) might be used as prognostic indicators for gastric carcinoma patients
This review will briefly address the peripheral and central sensitization mechanisms of airway neurons and will then focus on NGF signaling and its role in cough hypersensitivity.[review]
This study show evidence of variation in plasmatic beta-NGF expression during the progression of dementia.
NGF is functionally linked to beta-catenin (zeige CTNNB1 Proteine), promoting the migration of human ovarian cancer cells via the WNT (zeige WNT2 Proteine)/beta-catenin (zeige CTNNB1 Proteine) pathway.
Varicella zoster virus DNA replication is regulated in part by an NGF pathway that is PI3-kinase (zeige PIK3CA Proteine)-independent.
Many studies indicate that the only presence of NGF is unable to generate cell carcinogenesis, both in normal neuronal and non-neuronal cells/tissues. However, it cannot be excluded the possibility that the co-expression of NGF and pro-carcinogenic molecules might open to different consequence. [review]
the effect and underlying mechanisms of NGF/BDNF on the production of NPW in PC12 cells and hypothalamus, is reported.
This gene is a member of the NGF-beta family and encodes a secreted protein which homodimerizes and is incorporated into a larger complex. This protein has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in this gene have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of this gene's expression is associated with allergic rhinitis.
beta-nerve growth factor
, nerve growth factor beta
, nerve growth factor, beta polypeptide
, nerve growth factor
, beta-Nerve growth factor
, nerve growth factor beta subunit
, nerve growth factor, beta
, nerve growth factor, beta subunit
, Beta-nerve growth factor
, nerve growth factor B
, beta-beta-nerve growth factor