NGFB Protein

Produktnummer ABIN7489071

Produktdetails

Target: NGFB (Nerve Growth Factor beta (NGFB))

Protein-Typ: Recombinant

Spezies: Maus

Quelle: HEK-293 Cells

Verwendungszweck: ActiveMax® Mouse Beta-NGF Protein, Tag Free (MALS verified)

Sequenz: Ser 122 - Gly 241

Produktmerkmale: ActiveMax® Mouse Beta-NGF Protein, Tag Free is expressed from human 293 cells (HEK293). It contains AA Ser 122 - Gly 241 (Accession # P01139).

Reinheit: 95 %

Endotoxin-Niveau: 0.1 EU per μg

Güteklasse: MALS verified

Anwendungsinformationen

Kommentare:

This protein carries no "tag". The protein has a calculated MW of 13.5 kDa. The protein migrates as <14 kDa under reducing (R) condition (SDS-PAGE).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 20 mM NaAC, 150 mM NaCl, pH 5.5

Lagerung: -20 °C

Informationen zur Lagerung: -20°C

Antigendetails

Target: NGFB (Nerve Growth Factor beta (NGFB))

Andere Bezeichnung: Beta-NGF (NGFB Produkte)

Synonyme: NGFB Protein, ngfb Protein, ns:zft386 Protein, xx:zft386 Protein, zgc:109730 Protein, hsan5 Protein, beta-ngf Protein, Ngfb Protein, Beta-NGF Protein, HSAN5 Protein, beta-NGF Protein, nerve growth factor Protein, nerve growth factor b (beta polypeptide) Protein, beta-Nerve growth factor Protein, nerve growth factor (beta polypeptide) Protein, NGF Protein, ngfb Protein, FPV072 Protein, FPV076 Protein, ngf Protein, Ngf Protein

Hintergrund: Nerve growth factor beta (beta-NGF) is a neurotrophic factor that plays critical role in the development and maintenance of sensory and sympathetic neurons. The active form of human beta-NGF is is a noncovalently disulfide-linked homodimer, which is secreted and signals through the low affinity nerve growth factor receptor (LNGFR) and the tropomyosin receptor kinase A (TrkA) to activate PI3K, Ras, and PLC signaling pathways.

Molekulargewicht: 13.5 kDa

Pathways: NF-kappaB Signalweg, RTK Signalweg, Regulation of Cell Size