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Für Ihre Validierungsdaten erstatten wir Ihnen den vollen Kaufpreis. Ich möchte dieses Produkt validierenRelevance Score | ABIN | Application | Konjugat | Host | Isotype | Epitope | Hersteller | Clonality | References | Details |
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1 | ABIN967995 | IF IHC (zinc) IP WB | Mouse | IgG1 | AA 3-202 | Anmelden zum Anzeigen | 1-p150Glued | 5 |
General |
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Antigen | Dynactin 1 (DCTN1) Antikörper |
Epitop | AA 3-202 Alternativen |
Reaktivität | Huhn, Hund, Human, Maus, Ratte (Rattus) Alternativen |
Wirt | Maus Alternativen |
Klonalität (Klon) | |
Konjugat | Dieser Dynactin 1 Antikörper ist unkonjugiert Alternativen |
Applikation |
Immunofluorescence (IF), Immunohistochemistry (Zinc-fixed Sections) (IHC (zinc)), Immunoprecipitation (IP), Western Blotting (WB)
Alternativen
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5 Publikationen vorhanden |
Hersteller | Anmelden zum Anzeigen |
Produktdetails anti-Dynactin 1 AntikörperTarget Details Dynactin 1 Anwendungsinformationen Handhabung Referenzen für anti-Dynactin 1 Antikörper (ABIN967996) Bilder |
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Kreuzreaktivität | Human, Huhn, Hund, Maus |
Produktmerkmale |
1. Since applications vary, each investigator should titrate the reagent to obtain optimal results. 2. Please refer to us for technical protocols. 3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing. 4. Source of all serum proteins is from USDA inspected abattoirs located in the United States. |
Reinigung | The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. |
Immunogen | Rat p150 [Glued] aa. 3-202 |
Klon | 1-p150Glued |
Isotyp | IgG1 |
Target Details Dynactin 1Produktdetails anti-Dynactin 1 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-Dynactin 1 Antikörper (ABIN967996) Bilder zurück nach oben |
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Antigen | |
Andere Bezeichnung | p150 Glued (DCTN1 Antibody Abstract) |
Hintergrund | P150 [Glued] was identified as a polypeptide associated with cytoplasmic dynein, the minus-end-directed microtubule-based motor protein. p150 [Glued] is also a member of the oligomeric dynactin complex. Dynactin mediates dynein-driven vesicle motility, as well as lower eukaryote nuclear transport. p150 [Glued] bears significant homology to the product of the Glued gene in Drosophila. It has been shown in vitro to be a required activator of dynein-mediated transport along microtubules. The p150 [Glued] component of the dynactin complex binds to microtubules and the actin-like protein Centractin (Arp-1), another member of the dynactin complex. In the developing rat, p150 [Glued] is expressed at high levels in neural tissue. Microtubule bindings assays with selected constructs of p150 [Glued] indicate that amino acids 39-150 are required for microtubule association. This antibody is routinely tested by western blot analysis. |
Molekulargewicht | 150 kDa |
Pathways | M Phase, ER-Nucleus Signaling |
AnwendungsinformationenProduktdetails anti-Dynactin 1 Antikörper Target Details Dynactin 1 Handhabung Referenzen für anti-Dynactin 1 Antikörper (ABIN967996) Bilder zurück nach oben |
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Kommentare |
Related Products: ABIN968536, ABIN967389 |
Beschränkungen | Nur für Forschungszwecke einsetzbar |
HandhabungProduktdetails anti-Dynactin 1 Antikörper Target Details Dynactin 1 Anwendungsinformationen Referenzen für anti-Dynactin 1 Antikörper (ABIN967996) Bilder zurück nach oben |
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Format | Liquid |
Konzentration | 250 μg/mL |
Buffer | Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide. |
Konservierungsmittel | Sodium azide |
Vorsichtsmaßnahmen | This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
Lagerung | -20 °C |
Informationen zur Lagerung | Store undiluted at -20°C. |
Referenzen für anti-Dynactin 1 Antikörper (ABIN967996)Produktdetails anti-Dynactin 1 Antikörper Target Details Dynactin 1 Anwendungsinformationen Handhabung Bilder zurück nach oben |
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Produkt verwendet in: |
Kurzchalia: "Anthrax toxin rafts into cells." in: The Journal of cell biology, Vol. 160, Issue 3, pp. 295-6, 2003 Askham, Vaughan, Goodson, Morrison: "Evidence that an interaction between EB1 and p150(Glued) is required for the formation and maintenance of a radial microtubule array anchored at the centrosome." in: Molecular biology of the cell, Vol. 13, Issue 10, pp. 3627-45, 2002 Aumais, Tunstead, McNeil, Schaar, McConnell, Lin, Clark, Yu-Lee: "NudC associates with Lis1 and the dynein motor at the leading pole of neurons." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 21, Issue 24, pp. RC187, 2001 Tai, Chuang, Sung: "Cytoplasmic dynein regulation by subunit heterogeneity and its role in apical transport." in: The Journal of cell biology, Vol. 153, Issue 7, pp. 1499-509, 2001 King, Schroer: "Dynactin increases the processivity of the cytoplasmic dynein motor." in: Nature cell biology, Vol. 2, Issue 1, pp. 20-4, 2000 |
BilderProduktdetails anti-Dynactin 1 Antikörper Target Details Dynactin 1 Anwendungsinformationen Handhabung Referenzen für anti-Dynactin 1 Antikörper (ABIN967996) zurück nach oben |
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Bilder des Herstellers |