anti-Ratte (Rattus) GNAQ Antikörper für Immunofluorescence

Recommended GNAQ Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Guanine Nucleotide Binding Protein (G Protein), Q Polypeptide (GNAQ) Antikörper
  • si:ch73-270f14.2
  • CMC1
  • G-ALPHA-q
  • GAQ
  • SWS
  • Galphaq
  • Gnaq
  • g-alpha-q
  • gaq
  • gnaqb
  • 1110005L02Rik
  • 6230401I02Rik
  • AA408290
  • AW060788
  • Dsk1
  • Dsk10
  • Gq
  • GqI
  • guanine nucleotide binding protein (G protein), q polypeptide
  • G protein subunit alpha q
  • guanine nucleotide binding protein (G protein), q polypeptide S homeolog
  • guanine nucleotide binding protein, alpha q polypeptide
  • gnaq
  • GNAQ
  • Gnaq
  • gnaq.S
Epitop
AA 22-31
15
15
12
10
8
8
4
3
2
2
2
2
1
1
1
1
1
1
Reaktivität
Huhn, Hund, Human, Maus, Ratte (Rattus)
89
40
36
12
11
9
4
4
4
4
3
3
2
2
Wirt
Maus
63
18
8
Klonalität
Monoklonal
Konjugat
Dieser GNAQ Antikörper ist unkonjugiert
5
5
5
3
3
3
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (IF), Western Blotting (WB)
72
44
18
13
8
1
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Produktnummer ABIN968914
Preis und Verfügbarkeit auf Anfrage.
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
11.797404 ABIN968915 IF WB Mouse IgG1 AA 22-31 Anmelden zum Anzeigen 10-GAQ 3

General

Antigen Guanine Nucleotide Binding Protein (G Protein), Q Polypeptide (GNAQ) Antikörper
Epitop AA 22-31
(15), (15), (12), (10), (8), (8), (4), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Reaktivität Huhn, Hund, Human, Maus, Ratte (Rattus)
(89), (40), (36), (12), (11), (9), (4), (4), (4), (4), (3), (3), (2), (2)
Wirt Maus
(63), (18), (8)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser GNAQ Antikörper ist unkonjugiert
(5), (5), (5), (3), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Immunofluorescence (IF), Western Blotting (WB)
(72), (44), (18), (13), (8), (1), (1), (1)
Pubmed 3 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-GNAQ Antikörper

Target Details GNAQ Anwendungsinformationen Handhabung Referenzen für anti-GNAQ Antikörper (ABIN968914) Bilder
Kreuzreaktivität Maus, Ratte (Rattus), Huhn, Hund
Produktmerkmale 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
Reinigung The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Immunogen Human Galphaq aa. 22-31
Klon 10-GAQ
Isotyp IgG1

Target Details GNAQ

Produktdetails anti-GNAQ Antikörper Anwendungsinformationen Handhabung Referenzen für anti-GNAQ Antikörper (ABIN968914) Bilder zurück nach oben
Antigen
Andere Bezeichnung Galpha q (GNAQ Antibody Abstract)
Hintergrund The GTP binding regulatory proteins (G proteins) consist of three subunits: alpha, beta, and gamma. These heterotrimeric proteins function at membranes to relay signals from cell surface receptors to intracellular effectors. The alpha subunit is unique for each G protein and contains the site of GTP binding and hydrolysis, as well sites for receptor and effector interactions. The betagamma subunit complex interacts directly with receptors and the alpha subunit. The Galpha family includes four families: the Galphas family including Galphas , Galphao1f, and Galphat, the Galphai family including Galphai, Galphao, and Galphaz, the Galphaq/Galpha11 family and the Galpha12/13 family. The Galphaq protein is 88% homologus with Galpha11 and both are widely expressed. These G proteins activate phospholipase C proteins, which induce calcium signaling events. G protein coupled receptors (GPCRs) involved in regulating Wnt signaling activate Galphaq, phospholipase Cbeta, and induce calcium-dependent activation of calpain. These events promote beta-catenin nuclear export and proteolysis. Galphaq has also been implicated in metabotropic glutamate receptor signaling. Thus, Galphaq isoforms activate phospholipase C proteins in various G-protein coupled receptor pathways.
Molekulargewicht 42 kDa
Pathways JAK-STAT Signalweg, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction

Anwendungsinformationen

Produktdetails anti-GNAQ Antikörper Target Details GNAQ Handhabung Referenzen für anti-GNAQ Antikörper (ABIN968914) Bilder zurück nach oben
Kommentare

Related Products: ABIN968537, ABIN967389

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-GNAQ Antikörper Target Details GNAQ Anwendungsinformationen Referenzen für anti-GNAQ Antikörper (ABIN968914) Bilder zurück nach oben
Format Liquid
Konzentration 250 μg/mL
Buffer Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store undiluted at -20° C.

Referenzen für anti-GNAQ Antikörper (ABIN968914)

Produktdetails anti-GNAQ Antikörper Target Details GNAQ Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Dutt, Kjoller, Giel, Hall, Toksoz: "Activated Galphaq family members induce Rho GTPase activation and Rho-dependent actin filament assembly." in: FEBS letters, Vol. 531, Issue 3, pp. 565-9, 2002

Li, Iyengar: "Calpain as an effector of the Gq signaling pathway for inhibition of Wnt/beta -catenin-regulated cell proliferation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 20, pp. 13254-9, 2002

Strathmann, Simon: "G protein diversity: a distinct class of alpha subunits is present in vertebrates and invertebrates." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 87, Issue 23, pp. 9113-7, 1991

Bilder

Produktdetails anti-GNAQ Antikörper Target Details GNAQ Anwendungsinformationen Handhabung Referenzen für anti-GNAQ Antikörper (ABIN968914) zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Guanine Nucleotide Binding Protein (G Protein), Q Polypeptide (GNAQ) (AA 22-31) antibody (ABIN968914) Western blot analysis of Galphaq on a Jurkat cell lysate (Human T-cell leukemia, ATCC...
Immunofluorescence (IF) image for anti-Guanine Nucleotide Binding Protein (G Protein), Q Polypeptide (GNAQ) (AA 22-31) antibody (ABIN968914) Immunofluorescence staining of PC12 cells (Rat neuroblastoma, ATCC CRL-1721) treated ...