GNAQ Antikörper

Produktnummer ABIN6939535

Der Maus Monoklonal anti-GNAQ Antikörper wird verwendet zum Nachweis von GNAQ in Proben von Human. Er wurde validiert für ELISA, IF und FACS.

Kurzübersicht für GNAQ Antikörper (ABIN6939535)

Target: GNAQ (Guanine Nucleotide Binding Protein (G Protein), Q Polypeptide (GNAQ))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser GNAQ Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Klon: GNAQ-2434

Produktdetails anti-GNAQ Antikörper

Verwendungszweck: Guanine nucleotide-binding protein alpha-q / GNAQ / G-ALPHA-q Antibody

Spezifität: GNAQis 359 amino acids long and is identical in all but 1 amino acid residue to the Mouse protein. Analysis of human genomic DNA revealed an intronless sequence with strong homology to human GNAQ cDNA. In comparison to GNAQ cDNA, this genomic DNA sequence included several small deletions and insertions that altered the reading frame, multiple single based changes, and a premature termination codon in the open reading frame, all hallmarks of a processed pseudogene. Probes derived from human GNAQ cDNA sequence mapped both chromosomes 2 and 9 in higher constringency genomic blot analyses of DNA from a panel of human/rodent hybrid cell lines.

Aufreinigung: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant full-length human GNAQ protein

Isotyp: IgG2b, kappa

Anwendungsinformationen

Applikationshinweise:

Positive Control: HL-60, MOLT-4 and MCF-7 cells. Predominantly expressed in ovary, prostate, testis and colon.

Known Application: ELISA (For coating, order Ab without BSA), Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (0.5-1 μg/mL), Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu GNAQ

Target: GNAQ (Guanine Nucleotide Binding Protein (G Protein), Q Polypeptide (GNAQ))

Andere Bezeichnung: GNAQ

Hintergrund:

CMC1, G alpha Q, G protein alpha Q, GAQ, guanine nucleotide binding protein (G protein), q polypeptide, Guanine nucleotide-binding protein G(q) subunit alpha, SWS

HL-60, MOLT-4 and MCF-7 cells. Predominantly expressed in ovary, prostate, testis and colon.

Molekulargewicht: 45kDa

Gen-ID: 2776, 269782

UniProt: P50148

Pathways: JAK-STAT Signalweg, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction