anti-Ratte (Rattus) Adrenergic, Beta, Receptor Kinase 1 Antikörper für Western Blotting

Recommended Adrenergic, Beta, Receptor Kinase 1 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Adrenergic, Beta, Receptor Kinase 1 (ADRBK1) Antikörper
  • Adrbk-1
  • Bark-1
  • GRK2
  • betaARK1
  • BARK1
  • BETA-ARK1
  • GRK-2
  • Grk2
  • beta-adrenergic receptor kinase 1
  • G protein-coupled receptor kinase 2
  • Tsp_00497
  • grk2
  • Grk2
  • GRK2
Reaktivität
Maus, Ratte (Rattus), Human
156
91
85
17
12
12
9
5
4
3
3
1
1
1
1
Wirt
Kaninchen
116
28
17
2
Klonalität
Polyklonal
Konjugat
Unkonjugiert
5
5
5
1
1
1
Applikation
Immunohistochemistry (IHC), Western Blotting (WB)
145
98
77
25
20
12
5
5
3
1
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Bilder

Produktnummer ABIN3022346
$ 523.93
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
30.05837 ABIN969178 ICC IHC ELISA WB Mouse IgG1 Anmelden zum Anzeigen 3F8 2
19.802607 ABIN1845389 ELISA IF/ICC IHC WB Mouse IgG1 Anmelden zum Anzeigen 0
19.55837 ABIN3184940 ELISA IHC WB Rabbit IgG C-Term Anmelden zum Anzeigen Polyclonal 0
19.55837 ABIN3184941 ELISA WB Rabbit IgG Ser129 Anmelden zum Anzeigen Polyclonal 0
17.255764 ABIN966226 IF IHC ELISA WB Mouse IgG1 Anmelden zum Anzeigen 3F8 2
16.802607 ABIN2985863 IHC WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
16.55837 ABIN3182350 ELISA WB Rabbit IgG pSer685 Anmelden zum Anzeigen Polyclonal 0
16.55837 ABIN3184943 ELISA IHC WB Rabbit IgG Ser129 Anmelden zum Anzeigen Polyclonal 0
13.802607 ABIN4880192 ELISA ICC IHC WB Mouse IgG1 Anmelden zum Anzeigen 3F8 0
13.802607 ABIN6259807 ELISA ICC IF IHC WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
13.802607 ABIN1105519 EIA IF IHC (p) WB Mouse IgG1 Anmelden zum Anzeigen 3F8 0
12.755764 ABIN6390607 ELISA WB Rabbit IgG pSer685 Anmelden zum Anzeigen Polyclonal 0
12.755764 ABIN6390632 ELISA WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
12.755764 ABIN3182539 ELISA IHC WB Rabbit IgG pSer29 Anmelden zum Anzeigen Polyclonal 0
12.755764 ABIN4901624 ELISA IF IHC (p) WB Mouse IgG1 Anmelden zum Anzeigen 3F8 0
12.755764 ABIN2140917 ELISA WB Rabbit IgG pSer685 Anmelden zum Anzeigen Polyclonal 0
10.802607 ABIN2784714 WB Rabbit N-Term Anmelden zum Anzeigen Polyclonal 0
10.802607 ABIN2704864 IC IF IHC WB Rabbit C-Term Anmelden zum Anzeigen Polyclonal 0
10.802607 ABIN5965322 IHC WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
8.5 ABIN534096 IHC (fro) IF WB Mouse IgG1 Anmelden zum Anzeigen 5D5 3

General

Antigen Adrenergic, Beta, Receptor Kinase 1 (ADRBK1) Antikörper
Reaktivität Maus, Ratte (Rattus), Human
(156), (91), (85), (17), (12), (12), (9), (5), (4), (3), (3), (1), (1), (1), (1)
Wirt Kaninchen
(116), (28), (17), (2)
Klonalität
Polyklonal
Konjugat Unkonjugiert
(5), (5), (5), (1), (1), (1)
Applikation Immunohistochemistry (IHC), Western Blotting (WB)
(145), (98), (77), (25), (20), (12), (5), (5), (3), (1), (1), (1)
Hersteller Anmelden zum Anzeigen

Produktdetails

Antigendetails Anwendungsinformationen Handhabung Bilder
Reinigung Affinity purification
Immunogen Recombinant protein of human ADRBK1
Isotyp IgG

Antigendetails

Produktdetails Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung ADRBK1 (ADRBK1 Antibody Abstract)
Hintergrund G-protein-coupled receptor kinase 2 (GRK2), also known as beta-adrenergic receptor kinase 1 (beta-ARK1), is a member of the GRK family, which phosphorylates the activated form of G-protein-coupled receptors (GPCRs) and initiates the desensitization process of GPCR. GRK2 kinase activity and cellular localization are tightly regulated by interactions with activated receptors, G-beta and G-gamma subunits, adaptor proteins, phospholipids, caveolin and calmodulin, as well as by phosphorylation. PKC phosphorylation enhances GRK2 activity by promoting its membrane localization and by abolishing the inhibitory association of calmodulin. PKA phosphorylates GRK2 at Ser685, which facilitates the association of GRK2 with a beta-adrenergic receptor. Erk inhibits GRK2 activity via phosphorylation at Ser670. Src phosphorylates GRK2 at multiple tyrosine residues (Tyr13, 86 and 92), which activates GRK2 activity and promotes GRK2 degradation.
Synonyms: BARK1, BETA-ARK1, FLJ16718, GRK2
Gen-ID 156
UniProt P25098
Pathways EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling

Anwendungsinformationen

Produktdetails Antigendetails Handhabung Bilder zurück nach oben
Applikations-hinweise Recommended dilutions: WB: 1:500-1:2000, IHC: 1:50-1:200
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails Antigendetails Anwendungsinformationen Bilder zurück nach oben
Format Liquid
Buffer PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid freeze / thaw cycles
Lagerung -20 °C/-80 °C

Bilder

Produktdetails Antigendetails Anwendungsinformationen Handhabung zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Adrenergic, Beta, Receptor Kinase 1 (ADRBK1) antibody (ABIN3022346) Western blot analysis of extracts of various cell lines, using ADRBK1 antibody.
Western Blotting (WB) image for anti-Adrenergic, Beta, Receptor Kinase 1 (ADRBK1) antibody (ABIN3022346) Western blot analysis of extracts of various cell lines, using ADRBK1 antibody.
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Adrenergic, Beta, Receptor Kinase 1 (ADRBK1) antibody (ABIN3022346) Immunohistochemistry of paraffin-embedded rat brain using ADRBK1 Antibody.
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Adrenergic, Beta, Receptor Kinase 1 (ADRBK1) antibody (ABIN3022346) Immunohistochemistry of paraffin-embedded rat heart using ADRBK1 Antibody.
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Adrenergic, Beta, Receptor Kinase 1 (ADRBK1) antibody (ABIN3022346) Immunohistochemistry of paraffin-embedded human esophageal cancer using ADRBK1 Antibody.
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Adrenergic, Beta, Receptor Kinase 1 (ADRBK1) antibody (ABIN3022346) Immunohistochemistry of paraffin-embedded mouse kidney using ADRBK1 Antibody.