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GRK2 Antikörper

KO Validated ADRBK1 Reaktivität: Human, Maus, Ratte WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7259288
  • Target Alle GRK2 (ADRBK1) Antikörper anzeigen
    GRK2 (ADRBK1) (Adrenergic, Beta, Receptor Kinase 1 (ADRBK1))
    Reaktivität
    • 98
    • 77
    • 56
    • 8
    • 7
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    Human, Maus, Ratte
    Wirt
    • 92
    • 8
    • 2
    • 2
    Kaninchen
    Klonalität
    • 87
    • 17
    Polyklonal
    Konjugat
    • 58
    • 7
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser GRK2 Antikörper ist unkonjugiert
    Applikation
    • 56
    • 45
    • 30
    • 17
    • 14
    • 13
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Spezifität
    This antibody ist KO validated.
    Produktmerkmale
    Polyclonal Antibody
    Aufreinigung
    Affinity purification
    Güteklasse
    KO Validated
    Immunogen
    Recombinant fusion protein of human ADRBK1 (NP_001610.2).
    Isotyp
    IgG
    Top Product
    Discover our top product ADRBK1 Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000 IHC 1:50-1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    GRK2 (ADRBK1) (Adrenergic, Beta, Receptor Kinase 1 (ADRBK1))
    Andere Bezeichnung
    ADRBK1 (ADRBK1 Produkte)
    Synonyme
    Adrbk-1 antikoerper, Bark-1 antikoerper, GRK2 antikoerper, betaARK1 antikoerper, BARK1 antikoerper, BETA-ARK1 antikoerper, GRK-2 antikoerper, Grk2 antikoerper, beta-adrenergic receptor kinase 1 antikoerper, G protein-coupled receptor kinase 2 antikoerper, Tsp_00497 antikoerper, grk2 antikoerper, Grk2 antikoerper, GRK2 antikoerper
    Hintergrund
    The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.
    Molekulargewicht

    Observed_MW: 80 kDa

    Calculated_MW: 79 kDa

    Gen-ID
    156
    UniProt
    P25098
    Pathways
    EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling
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