anti-Ratte (Rattus) Adrenergic, Beta, Receptor Kinase 1 Antikörper für Immunohistochemistry (Paraffin-embedded Sections)
Recommended Adrenergic, Beta, Receptor Kinase 1 Antibody (geliefert von: Anmelden zum Anzeigen )
- Antigen
-
Adrenergic, Beta, Receptor Kinase 1 (ADRBK1) Antikörper
Synonyme für dieses Antigen anzeigen- Adrbk-1
- Bark-1
- GRK2
- betaARK1
- BARK1
- BETA-ARK1
- GRK-2
- Grk2
- beta-adrenergic receptor kinase 1
- G protein-coupled receptor kinase 2
- Tsp_00497
- grk2
- Grk2
- GRK2
- Reaktivität
-
Human, Maus, Ratte (Rattus)
Alternativen - Wirt
-
Kaninchen
Alternativen - Klonalität
- Konjugat
-
Unkonjugiert
Alternativen - Applikation
-
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
Alternativen - Hersteller
- Anmelden zum Anzeigen
- Hersteller Produkt- Nr.
- Anmelden zum Anzeigen
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Produktnummer ABIN499029
$ 390.50
Zzgl. Versandkosten $45.00
Zzgl. Versandkosten $45.00
| Relevance Score | ABIN | Application | Konjugat | Host | Isotype | Epitope | Hersteller | Clonality | References | Details |
|---|---|---|---|---|---|---|---|---|---|---|
| 12.811132 | ABIN4316203 | ELISA ICC IF IHC IHC (p) WB | Mouse | IgG1 | Anmelden zum Anzeigen | 3F8 | 0 | |||
| 12.811132 | ABIN4316200 | IHC IHC (p) | Rabbit | N-Term | Anmelden zum Anzeigen | Polyclonal | 0 | |||
| 1 | ABIN1498524 | ELISA ICC IF IHC (p) WB | Mouse | IgG1 | Anmelden zum Anzeigen | 3F8 | 0 | |||
| 1 | ABIN2888664 | IHC (p) ELISA | Rabbit | IgG | AA 14-63 | Anmelden zum Anzeigen | Polyclonal | 0 | ||
| 1 | ABIN271929 | IHC (p) WB | Rabbit | Anmelden zum Anzeigen | Polyclonal | 0 | ||||
| 1 | ABIN2893101 | IHC (p) WB | Rabbit | Val678 | Anmelden zum Anzeigen | Polyclonal | 0 | |||
| 1 | ABIN2883840 | ELISA IHC (p) WB | Rabbit | IgG | pSer29 | Anmelden zum Anzeigen | Polyclonal | 0 | ||
| 1 | ABIN2891686 | IHC (p) | Rabbit | pThr23 | Anmelden zum Anzeigen | Polyclonal | 0 | |||
| 1 | ABIN1105519 | EIA IF IHC (p) WB | Mouse | IgG1 | Anmelden zum Anzeigen | 3F8 | 0 | |||
| 1 | ABIN2604673 | IHC (p) WB | Rabbit | pSer29 | Anmelden zum Anzeigen | Polyclonal | 0 | |||
| 1 | ABIN2604674 | ICC IF IHC (p) WB | Rabbit | C-Term | Anmelden zum Anzeigen | Polyclonal | 0 | |||
| 1 | ABIN5682523 | ELISA ICC IF IHC IHC (p) WB | Mouse | IgG1 | AA 389-583 | Anmelden zum Anzeigen | 3F8 | 0 | ||
| 1 | ABIN4316205 | ELISA IHC IHC (p) | Rabbit | N-Term | Anmelden zum Anzeigen | Polyclonal | 0 | |||
| 1 | ABIN4316204 | ELISA IHC IHC (p) | Rabbit | N-Term | Anmelden zum Anzeigen | Polyclonal | 0 |
General |
|
|---|---|
| Antigen | Adrenergic, Beta, Receptor Kinase 1 (ADRBK1) Antikörper |
| Reaktivität | Human, Maus, Ratte (Rattus) Alternativen |
| Wirt | Kaninchen Alternativen |
| Klonalität | |
| Konjugat | Unkonjugiert Alternativen |
| Applikation |
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
Alternativen
|
| Hersteller | Anmelden zum Anzeigen |
ProduktdetailsAntigendetails Anwendungsinformationen Handhabung Bilder |
|
| Spezifität | This antibody detects endogenous levels of GRK 2 protein. (region surrounding Val678) |
| Kreuzreaktivität (Details) |
Species reactivity (expected):Mouse and Rat. Species reactivity (tested):Human. |
| Reinigung | Affinity chromatography |
| Reinheit | > 95 % by SDS-PAGE |
AntigendetailsProduktdetails Anwendungsinformationen Handhabung Bilder zurück nach oben |
|
| Antigen | |
| Andere Bezeichnung | beta-ARK-1 / ADRBK1 (ADRBK1 Antibody Abstract) |
| Hintergrund | Heterotrimeric G protein-mediated signal transduction is a dynamically regulated process with the intensity of signal decreasing over time despite the continued presence of the agonist. This phenomenon, referred to as agonistmediated desensitization, involves phosphorylation of the receptor by two classes of enzymes. The first are the second messenger-regulated kinases such as c-AMP dependent protein kinase A and protein kinase C. The second are the G protein-coupled receptor kinases (GRKs). At least seven members of the GRK family have been identified. These include rhodopsin kinase, GRK 1, two forms of β-adrenergic receptor kinase, GRK 2 (βARK, βARK1) and GRK 3 (βARK2), IT-11 (GRK 4), GRK 5, GRK 6 and GRK 7. Phosphorylation of receptors by GRKs appears to be strictly dependent on the receptor being in its agonist-activated state.Synonyms: BARK, BARK1, Beta-adrenergic receptor kinase 1, G-protein coupled receptor kinase 2, GRK2 |
| Molekulargewicht | approx. 80 kDa |
| Gen-ID | 156 |
| NCBI Accession | NP_001610 |
| UniProt | P25098 |
| Pathways | EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling |
AnwendungsinformationenProduktdetails Antigendetails Handhabung Bilder zurück nach oben |
|
| Applikationshinweise |
Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user. |
| Beschränkungen | Nur für Forschungszwecke einsetzbar |
HandhabungProduktdetails Antigendetails Anwendungsinformationen Bilder zurück nach oben |
|
| Konzentration | 1,0 mg/mL |
| Buffer | Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide |
| Konservierungsmittel | Sodium azide |
| Vorsichtsmaßnahmen | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
| Handhabung | Avoid repeated freezing and thawing. |
| Lagerung | 4 °C/-20 °C |
| Informationen zur Lagerung | Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. |
BilderProduktdetails Antigendetails Anwendungsinformationen Handhabung zurück nach oben |
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| Bilder des Herstellers |
Immunohistochemistry (IHC) analyzes of GRK 2 antibody in paraffin-embedded hum...
Western blot (WB) analysis of GRK 2 antibody in extracts from Jurkat cells.
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