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anti-Human Calcineurin B Antikörper:
anti-Rat (Rattus) Calcineurin B Antikörper:
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Data suggest an association between polymorphisms in PPP3CA, PPP3R1 and PPP3R2 and baseline levels or trainability of endurance phenotype traits.
PPP3RL gene localizes to human chromosome 9q22 and transcripts of PPP3RL gene are specifically expressed in the testis.
cyclosporin and tacrolimus exert significantly different effects on calcineurin activity in renal transplant patients with stable, well-functioning grafts
calcineurin B potentiates the activation of procaspase-3 by accelerating its proteolytic maturation
Here, we report that Cabin1 has additional CN binding domain in its 701-900 amino acid residues.
Data suggest that calcineurin may regulate the kinase activity of CDK4 in a cell cycle-dependent manner and may be an important component of the negative regulation of CDK4.
results indicate a role for Cn and calcium-dependent signal transduction in sleep and memory regulation.
calcineurin, upon activation by Ca(2+)-calmodulin, cooperates with other factors to negatively regulate Egf receptor signaling at the level of sprouty and the GTPase-activating protein Gap1
surgical-induced Osteoarthritis mice treated with a miR-146a inhibitor significantly alleviated the destruction of articular cartilage via targeting Camk2d and Ppp3r2.
this stusy demonstrates that male mice lacking Ppp3cc or Ppp3r2 genes (knockout mice) are infertile, with reduced sperm motility owing to an inflexible midpiece.
we report that calcineurin subunit B interacted with TLR4, which in turn led to phosphorylaiton of IRF3 and secretion of IFN-beta
The CnB could be of use as a prophylactic adjuvant as it is a human-derived safe agent and has immune-modulating effects that promote the control of cancer and infectious diseases.
Mice with genetic deletion of the calcineurin Abeta gene had a marked decrease in type II Na/Pi mRNA levels and remarkably did not show the expected increase in type II Na/Pi mRNA levels after the challenge of a low-Pi diet
By several different criteria, calcineurin is dispensable for B cell tolerance, indicating that this phosphatase complex modulates immunogenic, but not tolerogenic, responses in vivo.
calcineurin-mediated skeletal muscle reprogramming induces the expression of several transcription regulators that coordinate changes in the expression of genes for lipid and glucose metabolism
These results suggest that calcineurin-dependent dephosphorylation plays an important role in the mechanisms of action of antidepressants, providing a new starting point for developing improved therapeutic treatments for depression.
neuronal CaN plays an opposite role in the formation of contextual fear memories and the extinction of previously formed contextual fear memories
Together, these findings reveal a previously unknown mechanism for the control of emotional memory that depends on CaN and Zif268.
Deactivation of calcineurin/NFAT pathway-induced pathological hypertrophy is a preferential mechanism by which exercise training leads to the cardiac anti-remodelling effect in heart failure.
Calcineurin is a calcium-binding and calmodulin-binding protein found in all cells from yeast to mammals, and a calcium- dependent, calmodulin-stimulated protein phosphatase (By similarity).
, calcineurin B, type II (19kDa)
, calcineurin B-like protein
, calcineurin BII
, calcineurin subunit B type 2
, protein phosphatase 2B regulatory subunit 2
, protein phosphatase 3 (formerly 2B), regulatory subunit B (19kD), beta isoform (calcineurin B, type II)
, protein phosphatase 3 (formerly 2B), regulatory subunit B, 19kDa, beta isoform (calcineurin B, type II)
, protein phosphatase 3 (formerly 2B), regulatory subunit B, beta isoform
, protein phosphatase 3 regulatory subunit B beta isoform
, calcineurin B
, calcineurin B, type II
, protein phospatase 3, regulatory subunit B, alpha isoform,type 2
, protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type II)
, protein phosphatase 3, regulatory subunit B, beta isoform
, protein phosphatase 3 regulatory subunit B, beta
, calcineurin subunit B type 1
, protein phosphatase 2B regulatory subunit 1
, protein phosphatase 3 (formerly 2B), regulatory subunit B, alpha isoform
, protein phosphatase 3 regulatory subunit B alpha
, PP2B beta 2
, calcineurin B subunit
, protein phospatase 3, regulatory subunit B, alpha isoform (calcineurin B, type II)