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anti-Human NAIP Antikörper:
anti-Rat (Rattus) NAIP Antikörper:
anti-Mouse (Murine) NAIP Antikörper:
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Human Polyclonal NAIP Primary Antibody für ELISA - ABIN4234199
Vinzing, Eitel, Lippmann, Hocke, Zahlten, Slevogt, Nguessan, Günther, Schmeck, Hippenstiel, Flieger, Suttorp, Opitz: NAIP and Ipaf control Legionella pneumophila replication in human cells. in Journal of immunology (Baltimore, Md. : 1950) 2008
Homozygous absence of SMN1 (zeige SMN1 Antikörper) exons 7 and 8, or exon 7 only, was found in 80% of childhood spinal muscular atrophy patients. Of those patients, 45% were also deleted for NAIP exon 5.
NAIP expression is most abundant in M2 macrophages, while cIAP1 (zeige BIRC2 Antikörper) and cIAP2 (zeige BIRC3 Antikörper) show an inverse pattern of expression in polarized cells, cIAP2 (zeige BIRC3 Antikörper) is preferentially expressed in M1-macrophages and cIAP1 (zeige BIRC2 Antikörper) in M2-macrophages. IAP (zeige ALPI Antikörper) antagonist treatment of resting M0 macrophages preceding polarization stimulation, induced upregulation of NAIP in M2 and downregulation of cIAP1 (zeige BIRC2 Antikörper) in M1 and M2 but an induction of cIAP2 (zeige BIRC3 Antikörper) in M1 macrophages.
Deletion in NAIP gene is associated with spinal muscular atrophy.
NAIP and survivin (zeige BIRC5 Antikörper) expressions were significantly reduced following varicocele induction when compared to sham animals whereas PDRN-treated rats showed an increase in NAIP and survivin (zeige BIRC5 Antikörper) levels.
The copy numbers and gene structures of NAIP genes were different in Chinese spinal muscular atrophy patients and healthy controls
results revealed that SMN2 (zeige SMN1 Antikörper) and NAIP copy numbers significantly influenced the age at onset, risk of death, and life expectancy in the spinal muscular atrophy patients and that the effect of SMN2 (zeige SMN1 Antikörper) was more significant
human Naip functions to activate the inflammasome in response to flagellin (zeige FliC Antikörper), similar to murine Naip5 (zeige BIRC2 Antikörper)/6.
Modulation of chemotherapeutic drug resistance in neuroblastoma (zeige ARHGEF16 Antikörper) SK-N-AS cells by the neural apoptosis inhibitory protein and miR (zeige MLXIP Antikörper)-520f.
Copy number variations of SMN2 (zeige SMN1 Antikörper) and NAIP genes in patients are related to spinal muscular atrophy clinical types (P < 0.05).
/NAIP1 and NAIP2/5 formed a large oligomeric complex with NLRC4 (zeige NLRC4 Antikörper) in the presence of corresponding bacterial ligands, and could support reconstitution of the NLRC4 (zeige NLRC4 Antikörper) inflammasome in a ligand-specific manner.
identified an intronic region of the NAIP gene responding to TEAD1 (zeige TEAD1 Antikörper)/YAP (zeige YAP1 Antikörper) activity, suggesting that regulation of NAIP by TEAD1 (zeige TEAD1 Antikörper)/YAP (zeige YAP1 Antikörper) is at the transcriptional level
This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. This copy of the gene is full length\; additional copies with truncations and internal deletions are also present in this region of chromosome 5q13. It is thought that this gene is a modifier of spinal muscular atrophy caused by mutations in a neighboring gene, SMN1. The protein encoded by this gene contains regions of homology to two baculovirus inhibitor of apoptosis proteins, and it is able to suppress apoptosis induced by various signals. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
baculoviral IAP repeat-containing 1
, baculoviral IAP repeat-containing protein 1
, neuronal apoptosis inhibitory protein
, nucleotide-binding oligomerization domain, leucine rich repeat and BIR domain containing 1
, psi neuronal apoptosis inhibitory protein
, NLR family, apoptosis inhibitory protein 2
, baculoviral IAP repeat-containing 1b