Use your antibodies-online credentials, if available.
Keine Produkte auf Ihrer Vergleichsliste.
Ihr Warenkorb ist leer.
Alle Spezies anzeigen
Weitere Synonyme anzeigen
Wählen Sie die Spezies und Applikation aus
anti-Human NAIP Antikörper:
anti-Mouse (Murine) NAIP Antikörper:
anti-Rat (Rattus) NAIP Antikörper:
Sie gelangen zu unserer vorgefilterten Suche.
Human Polyclonal NAIP Primary Antibody für IF, WB - ABIN541228
Roy, Mahadevan, McLean, Shutler, Yaraghi, Farahani, Baird, Besner-Johnston, Lefebvre, Kang: The gene for neuronal apoptosis inhibitory protein is partially deleted in individuals with spinal muscular atrophy. in Cell 1995
Show all 3 Pubmed References
Human Polyclonal NAIP Primary Antibody für ELISA - ABIN4234199
Vinzing, Eitel, Lippmann, Hocke, Zahlten, Slevogt, Nguessan, Günther, Schmeck, Hippenstiel, Flieger, Suttorp, Opitz: NAIP and Ipaf control Legionella pneumophila replication in human cells. in Journal of immunology (Baltimore, Md. : 1950) 2008
Our present report implies that NAIP will have broad implications for ALS symptoms as a risk factor and a promising prognostic biomarker.
Data document a previously unknown localization of NAIP along the entire cytokinetic process whose dynamics exhibits a distinct behavior.
NAIP expression is most abundant in M2 macrophages, while cIAP1 and cIAP2 show an inverse pattern of expression in polarized cells, cIAP2 is preferentially expressed in M1-macrophages and cIAP1 in M2-macrophages. IAP antagonist treatment of resting M0 macrophages preceding polarization stimulation, induced upregulation of NAIP in M2 and downregulation of cIAP1 in M1 and M2 but an induction of cIAP2 in M1 macrophages.
Deletion in NAIP gene is associated with spinal muscular atrophy.
NAIP and survivin expressions were significantly reduced following varicocele induction when compared to sham animals whereas PDRN-treated rats showed an increase in NAIP and survivin levels.
The copy numbers and gene structures of NAIP genes were different in Chinese spinal muscular atrophy patients and healthy controls
results revealed that SMN2 and NAIP copy numbers significantly influenced the age at onset, risk of death, and life expectancy in the spinal muscular atrophy patients and that the effect of SMN2 was more significant
human Naip functions to activate the inflammasome in response to flagellin, similar to murine Naip5/6.
Modulation of chemotherapeutic drug resistance in neuroblastoma SK-N-AS cells by the neural apoptosis inhibitory protein and miR-520f.
Copy number variations of SMN2 and NAIP genes in patients are related to spinal muscular atrophy clinical types (P < 0.05).
/NAIP1 and NAIP2/5 formed a large oligomeric complex with NLRC4 in the presence of corresponding bacterial ligands, and could support reconstitution of the NLRC4 inflammasome in a ligand-specific manner.
identified an intronic region of the NAIP gene responding to TEAD1/YAP activity, suggesting that regulation of NAIP by TEAD1/YAP is at the transcriptional level
the NAIP5-NLRC4 inflammasome is induced by direct interactions with conserved N- and C-terminal regions of flagellin
NAIPFull gene duplication might have been evolutionary maintained, or even selected for, because it may confer an advantage to the host against flagellated bacteria
There is a close relationship between SMN2, NAIP and H4F5 gene copy number and spinal muscular atrophy disease severity
NOD domain is essential for effective inhibition of procaspase-9 and procaspase-3 cleavage by the NAIP protein in apoptosis.
an inhibitor of procaspase-9 preventing apoptosis at the initiation stage
Expression of NAIP may be associated with enhanced survival of prostate cancer in response to castration
Results provide the first structures of BIR domains from human NAIP and cIAP2.
NAIP gene deletion was higher in type I spinal muscular atrophy than in type U or V. In type I patients lacking the NAIP gene, deterioration in their respiratory function is more rapid than in those type I patients retaining the NAIP gene.
Homozygous absence of SMN1 exons 7 and 8, or exon 7 only, was found in 80% of childhood spinal muscular atrophy patients. Of those patients, 45% were also deleted for NAIP exon 5.
Naip1 is uniquely required to detect T3SS needle protein and Naip2 is uniquely required to detect T3SS inner rod protein, but neither Naip1 nor Naip2 is required for detection of flagellin.
These results provide definitive genetic evidence for the important physiological function of NAIPs in antibacterial defense and inflammatory damage-induced lethality in mice.
An epithelium-intrinsic defense axis recruits NAIP and the NLRC4 inflammasome to promote removal of epithelial cells compromised by pathogen invasion.
NAIP/NLRC4 oligomerize, assembling inflammasomes, in the presence of their cognate bacterial ligands.
In this study, the the type III secretion system needle protein protein is identified as the agonist for the orphan murine NAIP1 receptor
NAIP transcripts are present in the brain and spinal cord of stage E9.5-E14.5 embryos, and in the embryonic branchial arches, nasal epithelium, the future digits, and (at E16.5) in the lateral ventricle, vibrissae follicles, retina, and intestinal villi.
systemic administration of kainic acid rapidly elevates expression of mRNA encoding neuronal apoptosis inhibitor protein (NAIP) in the hippocampus and that this increase does not occur in mice that lack TNF receptors.
Akt-regulated expression of NAIP-1 counters Abeta-dependent neuronal cell death
Powerful effects of PAX2 on renal branching morphogenesis and final nephron number may be mediated by activation of Naip which then suppresses apoptosis in ureter bud cells.
Multiple, domesticated long terminal repeats (LTRs) of endogenous retroviral elements provide NAIP promoter function in human, mouse, and rat.
a role for NAIP in increasing the survival of cells undergoing terminal differentiation as well as the possibility that the protein serves as an intestinal pathogen recognition protein was suggested
This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. This copy of the gene is full length\; additional copies with truncations and internal deletions are also present in this region of chromosome 5q13. It is thought that this gene is a modifier of spinal muscular atrophy caused by mutations in a neighboring gene, SMN1. The protein encoded by this gene contains regions of homology to two baculovirus inhibitor of apoptosis proteins, and it is able to suppress apoptosis induced by various signals. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
baculoviral IAP repeat-containing protein 1
, neuronal apoptosis inhibitory protein
, nucleotide-binding oligomerization domain, leucine rich repeat and BIR domain containing 1
, psi neuronal apoptosis inhibitory protein
, baculoviral IAP repeat-containing 1
, baculoviral IAP repeat-containing 1a
, baculoviral IAP repeat-containing protein 1a
, neuronal apoptosis inhibitory protein 1