NAIP Antikörper (AA 750-850)

Produktnummer ABIN7268932

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch NAIP in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für NAIP Antikörper (AA 750-850) (ABIN7268932)

Target: NAIP (NLR Family, Apoptosis Inhibitory Protein (NAIP))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NAIP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-NAIP Antikörper

Bindungsspezifität: AA 750-850

Verwendungszweck: NAIP Rabbit pAb

Sequenz: LLRSIHFPIR GNKTSPRAHF SVLETCFDKS QVPTIDQDYA SAFEPMNEWE RNLAEKEDNV KSYMDMQRRA SPDLSTGYWK LSPKQYKIPC LEVDVNDIDV V

Kreuzreaktivität: Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 750-850 of human NAIP (NP_075043.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu NAIP

Target: NAIP (NLR Family, Apoptosis Inhibitory Protein (NAIP))

Andere Bezeichnung: NAIP

Hintergrund: This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. This copy of the gene is full length, additional copies with truncations and internal deletions are also present in this region of chromosome 5q13. It is thought that this gene is a modifier of spinal muscular atrophy caused by mutations in a neighboring gene, SMN1. The protein encoded by this gene contains regions of homology to two baculovirus inhibitor of apoptosis proteins, and it is able to suppress apoptosis induced by various signals. Alternative splicing and the use of alternative promoters results in multiple transcript variants.,NAIP,BIRC1,NLRB1,psiNAIP,Cell Biology & Developmental Biology,Apoptosis,NAIP

Gen-ID: 4671

UniProt: Q13075

Pathways: Apoptose, Inflammasome