anti-Pferd Caspase 1 Antikörper für Western Blotting

Recommended Caspase 1 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Caspase 1 (CASP1) Antikörper
  • ICE
  • IL1BC
  • P45
  • Il1bc
  • Ice
  • CASP1
  • CG5370
  • DCP-1
  • DCP1
  • Dcp1
  • Dmel\\CG5370
  • ccp1
  • dcp-1
  • dcp1
  • l(2)01862
  • l(2)02132
  • caspase 1
  • caspase 1, apoptosis-related cysteine peptidase
  • caspase 4, apoptosis-related cysteine peptidase
  • Death caspase-1
  • caspase-1
  • caspase
  • caspase recruitment domain-containing protein 16
  • caspase 4
  • CASP1
  • Casp1
  • CASP4
  • Dcp-1
  • Caspase1
  • LOC5564196
  • LOC451519
Epitop
Middle Region
36
16
14
10
10
10
10
9
8
7
6
5
4
4
4
3
3
3
3
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Pferd, Human, Kaninchen, Yeast (Saccharomyces cerevisiae)
268
103
81
8
3
2
1
1
1
1
1
Wirt
Kaninchen
256
40
8
2
Klonalität
Polyklonal
Konjugat
Dieser Caspase 1 Antikörper ist unkonjugiert
23
16
8
3
3
2
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Western Blotting (WB)
275
166
123
85
32
27
19
15
7
5
3
3
1
Optionen
Hersteller
Anmelden zum Anzeigen
Hersteller Produkt- Nr.
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Bilder

Produktnummer ABIN2787901
$ 289.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN575710 WB Rabbit AA 30-79 Anmelden zum Anzeigen Polyclonal 0

General

Antigen Caspase 1 (CASP1) Antikörper
Epitop Middle Region
(36), (16), (14), (10), (10), (10), (10), (9), (8), (7), (6), (5), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Pferd, Human, Kaninchen, Yeast (Saccharomyces cerevisiae)
(268), (103), (81), (8), (3), (2), (1), (1), (1), (1), (1)
Wirt Kaninchen
(256), (40), (8), (2)
Klonalität
Polyklonal
Konjugat Dieser Caspase 1 Antikörper ist unkonjugiert
(23), (16), (8), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Western Blotting (WB)
(275), (166), (123), (85), (32), (27), (19), (15), (7), (5), (3), (3), (1)
Hersteller Anmelden zum Anzeigen

Produktdetails anti-Caspase 1 Antikörper

Target Details Caspase 1 Anwendungsinformationen Handhabung Bilder
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN974471.
Sequenz LQTRVLNKEE MEKVKRENAT VMDKTRALID SVIPKGAQAC QICITYICEE
Homologie Horse: 79%, Human: 100%, Rabbit: 79%, Yeast: 100%
Produktmerkmale This is a rabbit polyclonal antibody against CASP1. It was validated on Western Blot.
Reinigung Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human CASP1
Plasmids, Primers & others

Target Details Caspase 1

Produktdetails anti-Caspase 1 Antikörper Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung CASP1 (CASP1 Antibody Abstract)
Hintergrund This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a cytokine involved in the processes such as inflammation, septic shock, and wound healing. This gene has been shown to induce cell apoptosis and may function in various developmental stages. Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease. Alternative splicing of this gene results in five transcript variants encoding distinct isoforms.
Alias Symbols: ICE, IL1BC, P45
Protein Interaction Partner: ced-3, ced-4, VAC14, BCL2L1, UBC, XK, PLA2G4B, IL33, IL1B, PARP1, BIRC3, TRAF2, CEBPB, TIRAP, CARD17, CARD16, CARD8, PLA2G4A, CDK11B, NLRP1, ATN1, ATXN3, PYCARD, NLRC4, NOD1, CASP14, RIPK2, PAK1, PARK2, NEDD4, BID, IL18, PSEN2, NFE2L2, AR, BCAP31, MAPT, L
Protein Size: 383
Molekulargewicht 10 kDa
Gen-ID 834
NCBI Accession NM_001223, NP_001214
UniProt P29466
Pathways Apoptose, Interferon-gamma Pathway, Positive Regulation of Endopeptidase Activity

Anwendungsinformationen

Produktdetails anti-Caspase 1 Antikörper Target Details Caspase 1 Handhabung Bilder zurück nach oben
Applikations-hinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 383 AA

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-Caspase 1 Antikörper Target Details Caspase 1 Anwendungsinformationen Bilder zurück nach oben
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Bilder

Produktdetails anti-Caspase 1 Antikörper Target Details Caspase 1 Anwendungsinformationen Handhabung zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Caspase 1 (CASP1) (Middle Region) antibody (ABIN2787901) WB Suggested Anti-CASP1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer:
Western Blotting (WB) image for anti-Caspase 1 (CASP1) (Middle Region) antibody (ABIN2787901) WB Suggested Anti-CASP1
Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500...