PEN2 Antikörper (N-Term)

Produktnummer ABIN929231

Produktdetails anti-PEN2 Antikörper

Target: PEN2 (PSENEN) (Presenilin Enhancer 2 Homolog (PSENEN))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PEN2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Maus

Aufreinigung: Purified

Immunogen: Psenen antibody was raised in rabbit using the N terminal of Psenen as the immunogen

Anwendungsinformationen

Applikationshinweise: Optimal conditions should be determined by the investigator.

Kommentare:

Psenen Blocking Peptide, catalog no. 33R-4973, is also available for use as a blocking control in assays to test for specificity of this Psenen antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu PEN2

Target: PEN2 (PSENEN) (Presenilin Enhancer 2 Homolog (PSENEN))

Andere Bezeichnung: Psenen (PSENEN Produkte)

Synonyme: MSTP064 antikoerper, PEN-2 antikoerper, PEN2 antikoerper, Psenen antikoerper, ACYPI006208 antikoerper, 1700023M09Rik antikoerper, Pen-2 antikoerper, RGD1312037 antikoerper, CG33198 antikoerper, Dmel\\CG33198 antikoerper, anon-AE003800.1 antikoerper, dPen-2 antikoerper, psenen antikoerper, pen-2 antikoerper, pen2 antikoerper, zgc:109727 antikoerper, presenilin enhancer gamma-secretase subunit antikoerper, presenilin enhancer 2 antikoerper, presenilin enhancer gamma secretase subunit antikoerper, Gamma-secretase subunit pen-2 antikoerper, presenilin enhancer antikoerper, presenilin enhancer gamma secretase subunit S homeolog antikoerper, PSENEN antikoerper, PEN2 antikoerper, Psenen antikoerper, pen-2 antikoerper, psenen.S antikoerper, psenen antikoerper

Hintergrund: Psenen is an essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents the last step of maturation of gamma-secretase, facilitating endoproteolysis of presenilin and conferring gamma-secretase activity. Synonyms: Polyclonal Psenen antibody, Anti-Psenen antibody, presenilin enhancer 2 homolog, C. elegans antibody, 1700023M09Rik antibody, MGC102026 antibody.

Pathways: Notch Signalweg, Neurotrophin Signalübertragung