PEN2 Antikörper

Produktnummer ABIN7269513

Produktdetails anti-PEN2 Antikörper

Target: PEN2 (PSENEN) (Presenilin Enhancer 2 Homolog (PSENEN))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser PEN2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Verwendungszweck: PEN2/PSENEN Rabbit mAb

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Monoclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthesized peptide derived from human PEN2/PSENEN

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PEN2

Target: PEN2 (PSENEN) (Presenilin Enhancer 2 Homolog (PSENEN))

Andere Bezeichnung: PSENEN (PSENEN Produkte)

Synonyme: MSTP064 antikoerper, PEN-2 antikoerper, PEN2 antikoerper, Psenen antikoerper, ACYPI006208 antikoerper, 1700023M09Rik antikoerper, Pen-2 antikoerper, RGD1312037 antikoerper, CG33198 antikoerper, Dmel\\CG33198 antikoerper, anon-AE003800.1 antikoerper, dPen-2 antikoerper, psenen antikoerper, pen-2 antikoerper, pen2 antikoerper, zgc:109727 antikoerper, presenilin enhancer gamma-secretase subunit antikoerper, presenilin enhancer 2 antikoerper, presenilin enhancer gamma secretase subunit antikoerper, Gamma-secretase subunit pen-2 antikoerper, presenilin enhancer antikoerper, presenilin enhancer gamma secretase subunit S homeolog antikoerper, PSENEN antikoerper, PEN2 antikoerper, Psenen antikoerper, pen-2 antikoerper, psenen.S antikoerper, psenen antikoerper

Hintergrund: Presenilins, which are components of the gamma-secretase protein complex, are required for intramembranous processing of some type I transmembrane proteins, such as the Notch proteins and the beta-amyloid precursor protein. Signaling by Notch receptors mediates a wide range of developmental cell fates. Processing of the beta-amyloid precursor protein generates neurotoxic amyloid beta peptides, the major component of senile plaques associated with Alzheimer's disease. This gene encodes a protein that is required for Notch pathway signaling, and for the activity and accumulation of gamma-secretase. Mutations resulting in haploinsufficiency for this gene cause familial acne inversa-2 (ACNINV2). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],MDS033, MSTP064, PEN-2, PEN2,Cell Biology & Developmental Biology,ErbB-HER Signaling Pathway,ESC Pluripotency and Differentiation,Neurodegenerative Diseases,Neurodegenerative Diseases Markers,Neurodegenerative Diseases_Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimers Disease,Neuroscience,Notch Signaling Pathway,Signal Transduction,PSENEN

Molekulargewicht: 13kDa

Gen-ID: 55851

UniProt: Q9NZ42

Pathways: Notch Signalweg, Neurotrophin Signalübertragung