CIITA Antikörper (C-Term)
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- Target Alle CIITA Antikörper anzeigen
- CIITA (Class II, Major Histocompatibility Complex, Transactivator (CIITA))
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Bindungsspezifität
- C-Term
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Reaktivität
- Maus, Ratte, Hund
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CIITA Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Kreuzreaktivität
- Ratte (Rattus), Hund
- Aufreinigung
- Purified
- Immunogen
- C2 TA antibody was raised in rabbit using the C terminal of C2 A as the immunogen
- Top Product
- Discover our top product CIITA Primärantikörper
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- Applikationshinweise
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WB: 0.125 µg/mL
Optimal conditions should be determined by the investigator. - Kommentare
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C2TA Blocking Peptide, catalog no. 33R-5700, is also available for use as a blocking control in assays to test for specificity of this C2TA antibody
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Konzentration
- Lot specific
- Buffer
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
- Handhabung
- Avoid repeated freeze/thaw cycles.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- Target
- CIITA (Class II, Major Histocompatibility Complex, Transactivator (CIITA))
- Andere Bezeichnung
- C2TA (CIITA Produkte)
- Synonyme
- CIITA antikoerper, C2ta antikoerper, EG669998 antikoerper, Gm9475 antikoerper, C2TA antikoerper, CIITAIV antikoerper, MHC2TA antikoerper, NLRA antikoerper, Mhc2ta antikoerper, class II, major histocompatibility complex, transactivator antikoerper, class II major histocompatibility complex transactivator antikoerper, MHC class II transactivator antikoerper, class II transactivator antikoerper, CIITA antikoerper, LOC710761 antikoerper, ciita antikoerper, LOC100443575 antikoerper, Ciita antikoerper, LOC100736732 antikoerper
- Hintergrund
- C2ta is essential for transcriptional activity of the HLA class II promoter, activation is via the proximal promoter. No DNA binding of in vitro translated CIITA was detected. C2ta may act in a coactivator-like fashion through protein-protein interactions by contacting factors binding to the proximal MHC class II promoter, to elements of the transcription machinery, or both. Alternatively it may activate HLA class II transcription by modifying proteins that bind to the MHC class II promoter. Synonyms: Polyclonal C2TA antibody, Anti-C2TA antibody.
- Pathways
- Cancer Immune Checkpoints
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