KLRC1 Antikörper (C-Term)

Produktnummer ABIN926709

Produktdetails anti-KLRC1 Antikörper

Target: KLRC1 (Killer Cell Lectin-Like Receptor Subfamily C, Member 1 (KLRC1))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KLRC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Purified

Immunogen: KLRC1 antibody was raised in rabbit using the C terminal of KLRC1 as the immunogen

Anwendungsinformationen

Applikationshinweise: Optimal conditions should be determined by the investigator.

Kommentare:

KLRC1 Blocking Peptide, catalog no. 33R-8511, is also available for use as a blocking control in assays to test for specificity of this KLRC1 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu KLRC1

Target: KLRC1 (Killer Cell Lectin-Like Receptor Subfamily C, Member 1 (KLRC1))

Andere Bezeichnung: KLRC1 (KLRC1 Produkte)

Synonyme: rNKG2A antikoerper, NKG2-A antikoerper, NKG2A antikoerper, KLRC1 antikoerper, CD159A antikoerper, NKG2 antikoerper, CD159a antikoerper, NKG2B antikoerper, killer cell lectin like receptor C1 antikoerper, NKG2-A/NKG2-B type II integral membrane protein-like antikoerper, killer cell lectin-like receptor subfamily C, member 3 antikoerper, killer cell lectin-like receptor subfamily C, member 1 antikoerper, Klrc1 antikoerper, KLRC1 antikoerper, NKG2A antikoerper, KLRC3 antikoerper

Hintergrund: Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed. Synonyms: Polyclonal KLRC1 antibody, Anti-KLRC1 antibody, killer cell lectin-like receptor subfamily C, member 1 antibody, CD159A antibody, MGC13374 antibody, MGC59791 antibody, NKG2 antibody, NKG2A antibody.