This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This KLRC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 180-206 amino acids from the C-terminal region of human KLRC1.
rNKG2A antikoerper, NKG2-A antikoerper, NKG2A antikoerper, KLRC1 antikoerper, CD159A antikoerper, NKG2 antikoerper, CD159a antikoerper, NKG2B antikoerper, killer cell lectin like receptor C1 antikoerper, NKG2-A/NKG2-B type II integral membrane protein-like antikoerper, killer cell lectin-like receptor subfamily C, member 3 antikoerper, killer cell lectin-like receptor subfamily C, member 1 antikoerper, Klrc1 antikoerper, KLRC1 antikoerper, NKG2A antikoerper, KLRC3 antikoerper
Hintergrund
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. This protein belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells.