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KLRC1 Antikörper (N-Term)

KLRC1 Reaktivität: Human WB, IF, ICC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2856611
  • Target Alle KLRC1 Antikörper anzeigen
    KLRC1 (Killer Cell Lectin-Like Receptor Subfamily C, Member 1 (KLRC1))
    Bindungsspezifität
    • 14
    • 10
    • 9
    • 8
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 55
    • 12
    • 1
    • 1
    • 1
    Human
    Wirt
    • 52
    • 8
    • 5
    Kaninchen
    Klonalität
    • 54
    • 10
    • 1
    Polyklonal
    Konjugat
    • 32
    • 7
    • 6
    • 5
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser KLRC1 Antikörper ist unkonjugiert
    Applikation
    • 45
    • 29
    • 15
    • 12
    • 6
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Kreuzreaktivität
    Rhesusaffen, Schimpanse
    Kreuzreaktivität (Details)
    Rhesus Monkey (100 %), Chimpanzee (100 %)
    Produktmerkmale
    Rabbit Polyclonal antibody to KLRC1 (killer cell lectin-like receptor subfamily C, member 1)
    KLRC1 antibody [N1N2], N-term
    Aufreinigung
    Purified by antigen-affinity chromatography.
    Immunogen
    Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human KLRC1. The exact sequence is proprietary.
    Isotyp
    IgG
    Top Product
    Discover our top product KLRC1 Primärantikörper
  • Applikationshinweise
    Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
    Kommentare

    Positive Control: A431 , HepG2

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.54 mg/mL
    Buffer
    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    Konservierungsmittel
    Thimerosal (Merthiolate)
    Vorsichtsmaßnahmen
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    KLRC1 (Killer Cell Lectin-Like Receptor Subfamily C, Member 1 (KLRC1))
    Andere Bezeichnung
    KLRC1 (KLRC1 Produkte)
    Synonyme
    rNKG2A antikoerper, NKG2-A antikoerper, NKG2A antikoerper, KLRC1 antikoerper, CD159A antikoerper, NKG2 antikoerper, CD159a antikoerper, NKG2B antikoerper, killer cell lectin like receptor C1 antikoerper, NKG2-A/NKG2-B type II integral membrane protein-like antikoerper, killer cell lectin-like receptor subfamily C, member 3 antikoerper, killer cell lectin-like receptor subfamily C, member 1 antikoerper, Klrc1 antikoerper, KLRC1 antikoerper, NKG2A antikoerper, KLRC3 antikoerper
    Hintergrund
    Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed.

    Cellular Localization: Membrane, Single-pass type II membrane protein
    Molekulargewicht
    26 kDa
    Gen-ID
    3821
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