KLRC1 Antikörper (N-Term)
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- Target Alle KLRC1 Antikörper anzeigen
- KLRC1 (Killer Cell Lectin-Like Receptor Subfamily C, Member 1 (KLRC1))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser KLRC1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Kreuzreaktivität
- Rhesusaffen, Schimpanse
- Kreuzreaktivität (Details)
- Rhesus Monkey (100 %), Chimpanzee (100 %)
- Produktmerkmale
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Rabbit Polyclonal antibody to KLRC1 (killer cell lectin-like receptor subfamily C, member 1)
KLRC1 antibody [N1N2], N-term - Aufreinigung
- Purified by antigen-affinity chromatography.
- Immunogen
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human KLRC1. The exact sequence is proprietary.
- Isotyp
- IgG
- Top Product
- Discover our top product KLRC1 Primärantikörper
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- Applikationshinweise
- Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
- Kommentare
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Positive Control: A431 , HepG2
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.54 mg/mL
- Buffer
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
- Konservierungsmittel
- Thimerosal (Merthiolate)
- Vorsichtsmaßnahmen
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- KLRC1 (Killer Cell Lectin-Like Receptor Subfamily C, Member 1 (KLRC1))
- Andere Bezeichnung
- KLRC1 (KLRC1 Produkte)
- Synonyme
- rNKG2A antikoerper, NKG2-A antikoerper, NKG2A antikoerper, KLRC1 antikoerper, CD159A antikoerper, NKG2 antikoerper, CD159a antikoerper, NKG2B antikoerper, killer cell lectin like receptor C1 antikoerper, NKG2-A/NKG2-B type II integral membrane protein-like antikoerper, killer cell lectin-like receptor subfamily C, member 3 antikoerper, killer cell lectin-like receptor subfamily C, member 1 antikoerper, Klrc1 antikoerper, KLRC1 antikoerper, NKG2A antikoerper, KLRC3 antikoerper
- Hintergrund
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Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed.
Cellular Localization: Membrane, Single-pass type II membrane protein - Molekulargewicht
- 26 kDa
- Gen-ID
- 3821
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