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KLRC1 Produkte

(Killer Cell Lectin-Like Receptor Subfamily C, Member 1, KLRC1)

Kategorien

Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed. [provided by RefSeq, Jul 2008].

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Ausgewählte KLRC1 Kategorien

KLRC1 Antikörper

High quality antibodies with extensive validation data.

KLRC1 ELISA Kits

Reliable ELISA kits for a wide range of species.

KLRC1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene KLRC1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
ReaktivitätHuman
ApplikationFACS, IF, IHC (p), WB
Validierungen
  • collections(6)
Kat. Nr.ABIN652569
Menge200 μL
ReaktivitätHuman
ApplikationICC, IF, IHC (p), WB
Validierungen
  • collections(3)
Kat. Nr.ABIN2856611
Menge100 μL
ReaktivitätHuman
ApplikationFACS, IHC, ELISA, WB
Validierungen
  • collections(3)
Kat. Nr.ABIN2488928
Menge200 μL

Empfohlene KLRC1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
ReaktivitätHuman
Analytical MethodQuantitative Sandwich ELISA
Validierungen
Kat. Nr.ABIN6730532
Menge96 tests
ReaktivitätMouse
Analytical MethodQuantitative Sandwich ELISA
Validierungen
Kat. Nr.ABIN6730533
Menge96 tests

Empfohlene KLRC1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
ReaktivitätHuman
SourceInsect Cells
Validierungen
  • collections(1)
Kat. Nr.ABIN3084436
Menge1 mg
ReaktivitätHuman
SourceInsect Cells
Validierungen
  • collections(1)
Kat. Nr.ABIN3084435
Menge0.5 mg
ReaktivitätHuman
SourceHEK-293 Cells
Validierungen
  • collections(1)
Kat. Nr.ABIN6938861
Menge100 μg

Neueste Publikationen zu unseren KLRC1 Produkten

Ojo, Sharma, Liu, Moreton, Checkley-Luttge, Gupta, Lee, Lee, Otegbeye, Sekaly, de Lima, Wald: "Membrane bound IL-21 based NK cell feeder cells drive robust expansion and metabolic activation of NK cells." in: Scientific reports, Vol. 9, Issue 1, pp. 14916, 2019 (PubMed). Von den Autoren verwendete Methode: Biochemical Assay (BCA) (Probematerial (Species): Human).

Zou, Zuo, Yang, Fan: "The ANXA1 released from intestinal epithelial cells alleviate DSS-induced colitis by improving NKG2A expression of Natural Killer cells." in: Biochemical and biophysical research communications, Vol. 478, Issue 1, pp. 213-20, 2016 (PubMed). (Probematerial (Species): Mouse (Murine)).

Gill, Peppa, Micco, Singh, Carey, Foster, Maini, Kennedy: "Interferon Alpha Induces Sustained Changes in NK Cell Responsiveness to Hepatitis B Viral Load Suppression In Vivo." in: PLoS pathogens, Vol. 12, Issue 8, pp. e1005788, 2016 (PubMed). Von den Autoren verwendete Methode: Flow Cytometry (FACS) (Probematerial (Species): Human).

Loyon, Picard, Mauvais, Queiroz, Mougey, Pallandre, Galaine, Mercier-Letondal, Kellerman, Chaput, Wijdenes, Adotévi, Ferrand, Romero, Godet, Borg: "IL-21-Induced MHC Class II+ NK Cells Promote the Expansion of Human Uncommitted CD4+ Central Memory T Cells in a Macrophage Migration Inhibitory Factor-Dependent Manner." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 197, Issue 1, pp. 85-96, 2016 (PubMed). Von den Autoren verwendete Methode: Flow Cytometry (FACS) (Probematerial (Species): Human).

Guo, Shen, Fu, Liu, Chen, Ni, Ye, Sun, Li, Tian, Wei: "CD3(bright)CD56(+) T cells associate with pegylated interferon-alpha treatment nonresponse in chronic hepatitis B patients." in: Scientific reports, Vol. 6, pp. 25567, 2016 (PubMed). Von den Autoren verwendete Methode: Flow Cytometry (FACS) (Probematerial (Species): Human).

Kruse, Hamann, Monecke, Cyganek, Elsner, Hübscher, Walter, Streckfuss-Bömeke, Guan, Dressel: "Human Induced Pluripotent Stem Cells Are Targets for Allogeneic and Autologous Natural Killer (NK) Cells and Killing Is Partly Mediated by the Activating NK Receptor DNAM-1." in: PLoS ONE, Vol. 10, Issue 5, pp. e0125544, 2015 (PubMed). Von den Autoren verwendete Methode: Flow Cytometry (FACS) (Probematerial (Species): Human).

Roberti, Juliá, Rocca, Amat, Bravo, Loza, Coló, Loza, Fabiano, Maino, Podhorzer, Fainboim, Barrio, Mordoh, Levy: "Overexpression of CD85j in TNBC patients inhibits Cetuximab-mediated NK-cell ADCC but can be restored with CD85j functional blockade." in: European journal of immunology, Vol. 45, Issue 5, pp. 1560-9, 2015 (PubMed). Von den Autoren verwendete Methode: Flow Cytometry (FACS) (Probematerial (Species): Human).

Zhao, Xu, Dai, Peng, Zhu, Shen, Zheng, Ran: "WNT5A transforms intestinal CD8αα⁺ IELs into an unconventional phenotype with pro-inflammatory features." in: BMC gastroenterology, Vol. 15, pp. 173, 2015 (PubMed). Von den Autoren verwendete Methode: Flow Cytometry (FACS) (Probematerial (Species): Mouse (Murine)).

Spallanzani, Torres, Avila, Ziblat, Iraolagoitia, Rossi, Domaica, Fuertes, Rabinovich, Zwirner: "Regulatory Dendritic Cells Restrain NK Cell IFN-γ Production through Mechanisms Involving NKp46, IL-10, and MHC Class I-Specific Inhibitory Receptors." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 5, pp. 2141-8, 2015 (PubMed). Von den Autoren verwendete Methode: Flow Cytometry (FACS) (Probematerial (Species): Human).

Picardi, Mengarelli, Marino, Gallo, Benevolo, Pescarmona, Cocco, Fraioli, Tremante, Petti, De Fabritiis, Giacomini: "Up-regulation of activating and inhibitory NKG2 receptors in allogeneic and autologous hematopoietic stem cell grafts." in: Journal of experimental & clinical cancer research : CR, Vol. 34, pp. 98, 2015 (PubMed). Von den Autoren verwendete Methode: Flow Cytometry (FACS) (Probematerial (Species): Human).

Synonyme und alternative Namen zu KLRC1

killer cell lectin like receptor C1 (Klrc1), killer cell lectin like receptor C1 (KLRC1), NKG2-A/NKG2-B type II integral membrane protein-like (NKG2A), killer cell lectin-like receptor subfamily C, member 3 (KLRC3), killer cell lectin-like receptor subfamily C, member 1 (KLRC1), killer cell lectin-like receptor subfamily C, member 1 (Klrc1), CD159a, CD159A, KLRC1, NKG2, NKG2-A, NKG2A, NKG2B, rNKG2A

Gen-IDs für verschiedene Spezies

GENE ID SPEZIES
29683 Rattus norvegicus
450131 Pan troglodytes
514897 Bos taurus
611325 Canis lupus familiaris
100126720 Papio anubis
100144622 Sus scrofa
3821 Homo sapiens
16641 Mus musculus
574146 Macaca mulatta

Bezeichner auf Proteinebene für KLRC1

  • natural killer cell protein group 2-A (NKG2A)
  • CD159 antigen-like family member A
  • NK cell receptor A
  • NKG2-A/B-activating NK receptor
  • NKG2-A/NKG2-B type II integral membrane protein
  • killer cell lectin-like receptor subfamily C, member 1
  • C-lectin type II protein
  • NKG2-1/B activating NK receptor
  • NKG2-A/B type II integral membrane protein
  • natural killer cell lectin
  • natural killer group protein 2
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