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Collagen IV Antikörper (AA 1401-1500) (Alexa Fluor 647)

COL4 Reaktivität: Human, Maus, Ratte, Kaninchen WB, FACS, IF (p), IF (cc) Wirt: Kaninchen Polyclonal Alexa Fluor 647
Produktnummer ABIN891720
  • Target Alle Collagen IV (COL4) Antikörper anzeigen
    Collagen IV (COL4) (Collagen, Type IV (COL4))
    Bindungsspezifität
    • 16
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1401-1500
    Reaktivität
    • 87
    • 42
    • 39
    • 23
    • 15
    • 10
    • 5
    • 2
    Human, Maus, Ratte, Kaninchen
    Wirt
    • 56
    • 26
    • 12
    Kaninchen
    Klonalität
    • 67
    • 27
    Polyklonal
    Konjugat
    • 45
    • 10
    • 7
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Dieser Collagen IV Antikörper ist konjugiert mit Alexa Fluor 647
    Applikation
    • 60
    • 45
    • 30
    • 28
    • 27
    • 25
    • 25
    • 24
    • 17
    • 9
    • 9
    • 8
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
    Spezifität
    This antibody has 79 % cross reactivity with Collagen alpha-5(IV) chain.
    Kreuzreaktivität
    Human, Maus, Kaninchen, Ratte
    Homologie
    Dog,Cow,Pig,Horse
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from mouse Collagen alpha-1(IV) chain
    Isotyp
    IgG
    Top Product
    Discover our top product COL4 Primärantikörper
  • Applikationshinweise
    FCM 1:20-100
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    Collagen IV (COL4) (Collagen, Type IV (COL4))
    Andere Bezeichnung
    Collagen 4 (COL4 Produkte)
    Synonyme
    collagen, type IV antikoerper, Let-2 antikoerper
    Hintergrund

    Synonyms: Bru, Raw, Svc, Col4a-1, Del(8)44H, Collagen alpha-1(IV) chain, Col4a1

    Background: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen. Arresten, comprising the C-terminal NC1 domain, inhibits angiogenesis and tumor formation. The C-terminal half is found to possess the anti-angiogenic activity. Specifically inhibits endothelial cell proliferation, migration and tube formation. Inhibits expression of hypoxia-inducible factor 1alpha and ERK1/2 and p38 MAPK activation. Ligand for alpha1/beta1 integrin (By similarity).

    Gen-ID
    12826
    UniProt
    P02463
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