Collagen IV Antikörper (AA 1401-1500) (Biotin)
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- Target Alle Collagen IV (COL4) Antikörper anzeigen
- Collagen IV (COL4) (Collagen, Type IV (COL4))
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Bindungsspezifität
- AA 1401-1500
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Reaktivität
- Human, Maus, Ratte, Kaninchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Collagen IV Antikörper ist konjugiert mit Biotin
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Applikation
- ELISA, Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Spezifität
- This antibody has 79 % cross reactivity with Collagen alpha-5(IV) chain.
- Kreuzreaktivität
- Human, Maus, Kaninchen, Ratte
- Homologie
- Dog,Cow,Pig,Horse
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from mouse Collagen alpha-1(IV) chain
- Isotyp
- IgG
- Top Product
- Discover our top product COL4 Primärantikörper
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- Applikationshinweise
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C for 12 months.
- Haltbarkeit
- 12 months
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- Target
- Collagen IV (COL4) (Collagen, Type IV (COL4))
- Andere Bezeichnung
- Collagen 4 (COL4 Produkte)
- Synonyme
- collagen, type IV antikoerper, Let-2 antikoerper
- Hintergrund
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Synonyms: Bru, Raw, Svc, Col4a-1, Del(8)44H, Collagen alpha-1(IV) chain, Col4a1
Background: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen. Arresten, comprising the C-terminal NC1 domain, inhibits angiogenesis and tumor formation. The C-terminal half is found to possess the anti-angiogenic activity. Specifically inhibits endothelial cell proliferation, migration and tube formation. Inhibits expression of hypoxia-inducible factor 1alpha and ERK1/2 and p38 MAPK activation. Ligand for alpha1/beta1 integrin (By similarity).
- Gen-ID
- 12826
- UniProt
- P02463
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