SREBF1 Antikörper (AA 1-100)

Produktnummer ABIN7270598

Produktdetails anti-SREBF1 Antikörper

Target: SREBF1 (Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1))

Bindungsspezifität: AA 1-100

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SREBF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Verwendungszweck: SREBP1 Rabbit pAb

Sequenz: MDEPPFSEAA LEQALGEPCD LDAALLTDIE GEVGAGRGRA NGLDAPRAGA DRGAMDCTFE DMLQLINNQD SDFPGLFDPP YAGSGAGGTD PASPDTSSPG

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SREBF1 (NP_001005291.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu SREBF1

Target: SREBF1 (Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1))

Andere Bezeichnung: SREBF1 (SREBF1 Produkte)

Synonyme: SREBP-1c antikoerper, SREBP1 antikoerper, bHLHd1 antikoerper, ADD-1 antikoerper, ADD1 antikoerper, D630008H06 antikoerper, SREBP-1 antikoerper, SREBP-1a antikoerper, SREBP1c antikoerper, Srebp1 antikoerper, SCREBP1 antikoerper, SREBP-1C antikoerper, SREBF1 antikoerper, srebp1 antikoerper, sterol regulatory element binding transcription factor 1 antikoerper, sterol regulatory element binding transcription factor 1 L homeolog antikoerper, sterol regulatory element binding protein-1 antikoerper, Sterol regulatory element Binding Protein antikoerper, SREBF1 antikoerper, Srebf1 antikoerper, srebf1.L antikoerper, SREBP-1 antikoerper, srebf1 antikoerper, sbp-1 antikoerper

Hintergrund: This gene encodes a transcription factor that binds to the sterol regulatory element-1 (SRE1), which is a decamer flanking the low density lipoprotein receptor gene and some genes involved in sterol biosynthesis. The protein is synthesized as a precursor that is attached to the nuclear membrane and endoplasmic reticulum. Following cleavage, the mature protein translocates to the nucleus and activates transcription by binding to the SRE1. Sterols inhibit the cleavage of the precursor, and the mature nuclear form is rapidly catabolized, thereby reducing transcription. The protein is a member of the basic helix-loop-helix-leucine zipper (bHLH-Zip) transcription factor family. This gene is located within the Smith-Magenis syndrome region on chromosome 17.,SREBF1,SREBP-1c,SREBP1,SREBP1a,bHLHd1,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Endocrine & Metabolism,Lipid Metabolism,Cholesterol Metabolism,AMPK Signaling Pathway,Warburg Effect,Endocrine and metabolic diseases,Obesity,Cardiovascular,Lipids,SREBF1

Molekulargewicht: 45kDa/48kDa/111kDa/113kDa/121kDa/124kDa

Gen-ID: 6720

UniProt: P36956

Pathways: AMPK Signaling, Caspase Kaskade in der Apoptose, Negative Regulation of Hormone Secretion, Regulation of Lipid Metabolism by PPARalpha