SREBF1 Antikörper (pSer439)
Kurzübersicht für SREBF1 Antikörper (pSer439) (ABIN6255339)
Target
Alle SREBF1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- pSer439
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Verwendungszweck
- Phospho-SREBP1 (Ser439) Antibody
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Spezifität
- Phospho-SREBP1 (Ser439) Antibody detects endogenous levels of SREBP1 only when phosphorylated at Serine 439.
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Homologie
- Pig,Horse,Sheep,Dog
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Aufreinigung
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.
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Immunogen
- A synthesized peptide derived from human SREBP1 around the phosphorylation site of Ser439.
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Isotyp
- IgG
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anti-Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1) (AA 349-378) antibody
SREBF1 Reaktivität: Human WB, IHC (p), FACS Wirt: Kaninchen Polyclonal RB21265 unconjugated
anti-Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1) (AA 38-201) antibodySREBF1 Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1) (AA 801-900) antibodySREBF1 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 4B10 unconjugated
anti-Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1) (AA 1-100) antibodySREBF1 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1) (AA 158-390) antibodySREBF1 Reaktivität: Maus IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1) (Middle Region) antibodySREBF1 Reaktivität: Human, Ratte, Maus, Schwein, Rind (Kuh) WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1) (AA 461-510) antibodySREBF1 Reaktivität: Human, Ratte, Rind (Kuh), Ziege, Pferd, Hamster WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1) (Middle Region) antibodySREBF1 Reaktivität: Human, Ratte, Maus, Rind (Kuh), Ziege, Pferd WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1) antibodySREBF1 Reaktivität: Human IHC Wirt: Maus Monoclonal SREBP1-1578 unconjugated
anti-Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1) (AA 250-330) antibodySREBF1 Reaktivität: Human, Ratte, Maus, Syrischer Goldhamster WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
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Haltbarkeit
- 12 months
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- SREBF1 (Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1))
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Andere Bezeichnung
- SREBP1
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Hintergrund
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Description: Transcriptional activator required for lipid homeostasis. Regulates transcription of the LDL receptor gene as well as the fatty acid and to a lesser degree the cholesterol synthesis pathway (By similarity). Binds to the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3'). Has dual sequence specificity binding to both an E-box motif (5'-ATCACGTGA-3') and to SRE-1 (5'-ATCACCCCAC-3').
Gene: SREBF1
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Molekulargewicht
- 122kDa
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Gen-ID
- 6720
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UniProt
- P36956
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Pathways
- AMPK Signaling, Caspase Kaskade in der Apoptose, Negative Regulation of Hormone Secretion, Regulation of Lipid Metabolism by PPARalpha
Target
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