SREBF1 Antikörper (AA 38-201)

Produktnummer ABIN7170778

Produktdetails anti-SREBF1 Antikörper

Target: SREBF1 (Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1))

Bindungsspezifität: AA 38-201

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SREBF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Sterol regulatory element-binding protein 1 protein (38-201AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:1000-1:5000, IHC:1:200-1:500, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu SREBF1

Target: SREBF1 (Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1))

Andere Bezeichnung: SREBF1 (SREBF1 Produkte)

Synonyme: SREBP-1c antikoerper, SREBP1 antikoerper, bHLHd1 antikoerper, ADD-1 antikoerper, ADD1 antikoerper, D630008H06 antikoerper, SREBP-1 antikoerper, SREBP-1a antikoerper, SREBP1c antikoerper, Srebp1 antikoerper, SCREBP1 antikoerper, SREBP-1C antikoerper, SREBF1 antikoerper, srebp1 antikoerper, sterol regulatory element binding transcription factor 1 antikoerper, sterol regulatory element binding transcription factor 1 L homeolog antikoerper, sterol regulatory element binding protein-1 antikoerper, Sterol regulatory element Binding Protein antikoerper, SREBF1 antikoerper, Srebf1 antikoerper, srebf1.L antikoerper, SREBP-1 antikoerper, srebf1 antikoerper, sbp-1 antikoerper

Hintergrund:

Background: Transcriptional activator required for lipid homeostasis. Regulates transcription of the LDL receptor gene as well as the fatty acid and to a lesser degree the cholesterol synthesis pathway (By similarity). Binds to the sterol regulatory element 1 (SRE-1) (5\\\'-ATCACCCCAC-3\\\'). Has dual sequence specificity binding to both an E-box motif (5\\\'-ATCACGTGA-3\\\') and to SRE-1 (5\\\'-ATCACCCCAC-3\\\').

Aliases: ADD 1 antibody, bHLHd1 antibody, Class D basic helix-loop-helix protein 1 antibody, D630008H06 antibody, Processed sterol regulatory element-binding protein 1 antibody, SRBP1_HUMAN antibody, SREBF 1 antibody, SREBF1 antibody, SREBP 1 antibody, SREBP 1c antibody, SREBP-1 antibody, SREBP1 antibody, Sterol regulatory element binding protein 1 antibody, Sterol Regulatory Element Binding Transcription Factor 1 / Protein 1 antibody, Sterol regulatory element binding transcription factor 1 antibody, Sterol regulatory element-binding transcription factor 1 antibody

UniProt: P36956

Pathways: AMPK Signaling, Caspase Kaskade in der Apoptose, Negative Regulation of Hormone Secretion, Regulation of Lipid Metabolism by PPARalpha