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Phospholipase C gamma 1 Antikörper (pSer1248)
PLCG1
Reaktivität: Human
WB, IHC
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN7269347
Produktdetails anti-Phospholipase C gamma 1 Antikörper
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Target
Alle Phospholipase C gamma 1 (PLCG1) Antikörper anzeigen
Phospholipase C gamma 1 (PLCG1)
(phospholipase C, gamma 1 (PLCG1))
Bindungsspezifität
Alle Epitope für Phospholipase C gamma 1 Antikörper
pSer1248
Reaktivität
Alle Reaktivitäten für Phospholipase C gamma 1 Antikörper
Human
Wirt
Alle Wirte für Phospholipase C gamma 1 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für Phospholipase C gamma 1 Antikörper
Polyklonal
Konjugat
Alle Konjugate für Phospholipase C gamma 1 Antikörper
Dieser Phospholipase C gamma 1 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für Phospholipase C gamma 1 Antikörper
Western Blotting (WB), Immunohistochemistry (IHC)
Verwendungszweck
Phospho-PLC gamma 1 (PLCG1)-S1248 Rabbit pAb
Sequenz
REGSF
Kreuzreaktivität
Human, Maus, Ratte
Produktmerkmale
Phosphorylated Antibodies
Aufreinigung
Affinity purification
Immunogen
A synthetic phosphorylated peptide around S1248 of human PLC gamma 1 (PLCG1) (NP_002651.2).
Isotyp
IgG
Top Product
Discover our top product PLCG1 Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
WB,1:500 - 1:2000,IHC,1:10 - 1:100
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20°C. Avoid freeze / thaw cycles.
Details zu Phospholipase C gamma 1
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Target
Phospholipase C gamma 1 (PLCG1)
(phospholipase C, gamma 1 (PLCG1))
Andere Bezeichnung
PLCG1 (PLCG1 Produkte )
Synonyme
NCKAP3 antikoerper, PLC-II antikoerper, PLC1 antikoerper, PLC148 antikoerper, PLCgamma1 antikoerper, plc1 antikoerper, nckap3 antikoerper, plc-ii antikoerper, plc148 antikoerper, plcgamma1 antikoerper, PPLCA antikoerper, AI894140 antikoerper, Cded antikoerper, Plc-1 antikoerper, Plc-gamma1 antikoerper, Plcg-1 antikoerper, fj46f04 antikoerper, wu:fj46f04 antikoerper, wu:fj57a05 antikoerper, phospholipase C gamma 1 antikoerper, phospholipase C gamma 1 L homeolog antikoerper, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 antikoerper, phospholipase C, gamma 1 antikoerper, PLCG1 antikoerper, plcg1.L antikoerper, LOC100633163 antikoerper, Plcg1 antikoerper, plcg1 antikoerper
Hintergrund
The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene.,PLCG1,NCKAP3,PLC-II,PLC1,PLC148,PLCgamma1,Cancer,Signal Transduction,Phospholipase Signaling Pathway,ErbB-HER Signaling Pathway,MAPK-Erk Signaling Pathway,Cell Biology & Developmental Biology,Cytoskeleton,Actins,Endocrine & Metabolism,Lipid Metabolism,Hydrolysis,Immunology & Inflammation,T Cell Receptor Signaling Pathway,Cardiovascular,Angiogenesis,Lipids,Protein phosphorylation,PLCG1
Molekulargewicht
148kDa
Gen-ID
5335
UniProt
P19174
Pathways
RTK Signalweg , WNT Signalweg , T-Zell Rezeptor Signalweg , Fc-epsilon Rezeptor Signalübertragung , EGFR Signaling Pathway , Neurotrophin Signalübertragung , Thyroid Hormone Synthesis , Inositol Metabolic Process , Myometrial Relaxation and Contraction , Regulation of Muscle Cell Differentiation , Regulation of G-Protein Coupled Receptor Protein Signaling , Skeletal Muscle Fiber Development , G-protein mediated Events , Signaling Events mediated by VEGFR1 and VEGFR2 , Interaction of EGFR with phospholipase C-gamma , VEGFR1 Specific Signals , VEGF Signaling
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