IL1R2 Antikörper (AA 14-343)

Produktnummer ABIN7193772

Produktdetails anti-IL1R2 Antikörper

Target: IL1R2 (Interleukin 1 Receptor, Type II (IL1R2))

Bindungsspezifität: AA 14-343

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IL1R2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human CD121B (AA: extra 14-343) expressed in HEK293-6e cells supernatant.

Klon: 3G1D8

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: WB:1:500 - 1:2000, FCM:1:200 - 1:400, ELISA:1:10000,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Details zu IL1R2

Target: IL1R2 (Interleukin 1 Receptor, Type II (IL1R2))

Andere Bezeichnung: CD121B (IL1R2 Produkte)

Synonyme: CD121b antikoerper, CDw121b antikoerper, IL-1R-2 antikoerper, IL-1RT-2 antikoerper, IL-1RT2 antikoerper, IL1R2c antikoerper, IL1RB antikoerper, Il1r-2 antikoerper, IL-1R2 antikoerper, interleukin 1 receptor type 2 antikoerper, interleukin 1 receptor, type II antikoerper, interleukin-like antikoerper, IL1R2 antikoerper, Il1r2 antikoerper, KK34 antikoerper

Hintergrund:

Description: The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Alternative splicing results in multiple transcript variants and protein isoforms. Alternative splicing produces both membrane-bound and soluble proteins. A soluble protein is also produced by proteolytic cleavage.

Aliases: IL1R2,IL1RB, IL1R2c, CDw121b, IL-1R-2, IL-1RT2, IL-1RT-2

Molekulargewicht: 45.4 kDa

Gen-ID: 7850

Pathways: NF-kappaB Signalweg