IL1R2 Antikörper (AA 79-219)

Produktnummer ABIN7156768

Produktdetails anti-IL1R2 Antikörper

Target: IL1R2 (Interleukin 1 Receptor, Type II (IL1R2))

Bindungsspezifität: AA 79-219

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL1R2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität: Human, Ratte

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Interleukin-10 receptor subunit beta protein (79-219AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:5000, IHC:1:500-1:1000, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu IL1R2

Target: IL1R2 (Interleukin 1 Receptor, Type II (IL1R2))

Andere Bezeichnung: IL1RB (IL1R2 Produkte)

Synonyme: CD121b antikoerper, CDw121b antikoerper, IL-1R-2 antikoerper, IL-1RT-2 antikoerper, IL-1RT2 antikoerper, IL1R2c antikoerper, IL1RB antikoerper, Il1r-2 antikoerper, IL-1R2 antikoerper, interleukin 1 receptor type 2 antikoerper, interleukin 1 receptor, type II antikoerper, interleukin-like antikoerper, IL1R2 antikoerper, Il1r2 antikoerper, KK34 antikoerper

Hintergrund:

Background: Shared cell surface receptor required for the activation of five class 2 cytokines: IL10, IL22, IL26, IL28, and IFNL1. The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway leading to the expression of IFN-stimulated genes (ISG), which contribute to the antiviral state.

Aliases: Cd210 antibody, CDw210b antibody, CRF2 4 antibody, CRF2-4 antibody, CRFB4 antibody, Cytokine receptor class II antibody, Cytokine receptor class II CRF2 4 antibody, Cytokine receptor class-II member 4 antibody, Cytokine receptor family 2 member 4 antibody, Cytokine receptor family II member 4 antibody, D21S58 antibody, D21S66 antibody, I10R2_HUMAN antibody, IL-10 receptor subunit beta antibody, IL-10R subunit 2 antibody, IL-10R subunit beta antibody, IL-10R2 antibody, IL-10RB antibody, IL10R2 antibody, IL10RB antibody, Interleukin 10 receptor beta antibody, Interleukin-10 receptor subunit 2 antibody, Interleukin-10 receptor subunit beta antibody

UniProt: Q08334

Pathways: NF-kappaB Signalweg