IL1R2 Antikörper (AA 20-320)

Produktnummer ABIN7156749

Produktdetails anti-IL1R2 Antikörper

Target: IL1R2 (Interleukin 1 Receptor, Type II (IL1R2))

Bindungsspezifität: AA 20-320

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL1R2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Kreuzreaktivität: Human, Maus

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Interleukin-1 receptor type 2 protein (20-320AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:200-1:1000,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu IL1R2

Target: IL1R2 (Interleukin 1 Receptor, Type II (IL1R2))

Andere Bezeichnung: IL1R2 (IL1R2 Produkte)

Synonyme: CD121b antikoerper, CDw121b antikoerper, IL-1R-2 antikoerper, IL-1RT-2 antikoerper, IL-1RT2 antikoerper, IL1R2c antikoerper, IL1RB antikoerper, Il1r-2 antikoerper, IL-1R2 antikoerper, interleukin 1 receptor type 2 antikoerper, interleukin 1 receptor, type II antikoerper, interleukin-like antikoerper, IL1R2 antikoerper, Il1r2 antikoerper, KK34 antikoerper

Hintergrund:

Background: Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competetive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted IL1RAP with high affinity, this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors.

Aliases: IL1 Receptor II antibody, Antigen CDw121b antibody, CD121 antibody, CD121 antigen-like family member B antibody, CD121b antibody, CD121B Antigen antibody, CDw121b antibody, IL 1 type II receptor antibody, IL-1R-2 antibody, IL-1R-beta antibody, IL-1R2 antibody, IL-1RT-2 antibody, IL-1RT2 antibody, IL1R Beta antibody, Il1r-2 antibody, IL1R2 antibody, IL1R2_HUMAN antibody, IL1R2c antibody, IL1RB antibody, Interleukin 1 receptor type II variant 3 antibody, Interleukin 1 receptor, beta, type II antibody, Interleukin 1 receptor, type II antibody, Interleukin-1 receptor beta antibody, Interleukin-1 receptor type 2 antibody, Interleukin-1 receptor type II antibody, MGC137383 antibody, MGC47725 antibody, OTTHUMP00000207969 antibody, p68 antibody, Type II interleukin-1 receptor, beta antibody

UniProt: P27930

Pathways: NF-kappaB Signalweg