FZD6 Antikörper
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- Target Alle FZD6 Antikörper anzeigen
- FZD6 (Frizzled Family Receptor 6 (FZD6))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser FZD6 Antikörper ist unkonjugiert
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Applikation
- ELISA, Immunohistochemistry (IHC)
- Kreuzreaktivität
- Human, Maus
- Aufreinigung
- Antigen affinity purification
- Immunogen
- Synthetic peptide of Human FZD6
- Isotyp
- IgG
- Top Product
- Discover our top product FZD6 Primärantikörper
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- Applikationshinweise
- ELISA:1:2000-1:10000, IHC:1:100-1:300,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- FZD6 (Frizzled Family Receptor 6 (FZD6))
- Andere Bezeichnung
- FZD6 (FZD6 Produkte)
- Synonyme
- zgc:65879 antikoerper, zgc:77440 antikoerper, fz6 antikoerper, frz6 antikoerper, Xfrz6 antikoerper, frizzled6 antikoerper, frizzled-6 antikoerper, FZ-6 antikoerper, FZ6 antikoerper, HFZ6 antikoerper, NDNC10 antikoerper, Frizzled-6 antikoerper, Fz6 antikoerper, frizzled class receptor 6 antikoerper, frizzled class receptor 6 S homeolog antikoerper, fzd6 antikoerper, fzd6.S antikoerper, FZD6 antikoerper, Fzd6 antikoerper
- Hintergrund
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Background: This gene represents a member of the 'frizzled' gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting the processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis. Alternative splicing results in multiple transcript variants, some of which do not encode a protein with a predicted signal peptide.
Aliases: Frizzled 6 seven transmembrane spanning receptor antibody, Frizzled drosophila homolog of 6 antibody, Frizzled family receptor 6 antibody, Frizzled homolog 6 (Drosophila) antibody, Frizzled homolog 6 antibody, Frizzled-6 antibody, Frizzled6 antibody, Fz 6 antibody, Fz-6 antibody, Fz6 antibody, FZD 6 antibody, Fzd6 antibody, FZD6_HUMAN antibody, Hfz 6 antibody, hFz6 antibody, NDNC10 antibody
- UniProt
- O60353
- Pathways
- WNT Signalweg, Tube Formation
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