FZD6 Antikörper
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- Target Alle FZD6 Antikörper anzeigen
- FZD6 (Frizzled Family Receptor 6 (FZD6))
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Reaktivität
- Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser FZD6 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Produktmerkmale
- Polyclonal Antibody
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant fusion protein of human FZD6 (NP_003497.2).
- Isotyp
- IgG
- Top Product
- Discover our top product FZD6 Primärantikörper
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- Applikationshinweise
- WB 1:1000-1:2000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- FZD6 (Frizzled Family Receptor 6 (FZD6))
- Andere Bezeichnung
- FZD6 (FZD6 Produkte)
- Synonyme
- zgc:65879 antikoerper, zgc:77440 antikoerper, fz6 antikoerper, frz6 antikoerper, Xfrz6 antikoerper, frizzled6 antikoerper, frizzled-6 antikoerper, FZ-6 antikoerper, FZ6 antikoerper, HFZ6 antikoerper, NDNC10 antikoerper, Frizzled-6 antikoerper, Fz6 antikoerper, frizzled class receptor 6 antikoerper, frizzled class receptor 6 S homeolog antikoerper, fzd6 antikoerper, fzd6.S antikoerper, FZD6 antikoerper, Fzd6 antikoerper
- Hintergrund
- This gene represents a member of the 'frizzled' gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting the processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis. Alternative splicing results in multiple transcript variants, some of which do not encode a protein with a predicted signal peptide.
- Molekulargewicht
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Observed_MW: 79 kDa
Calculated_MW: 75 kDa/79 kDa
- Gen-ID
- 8323
- UniProt
- O60353
- Pathways
- WNT Signalweg, Tube Formation
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