FZD6 Produkte
(Frizzled Family Receptor 6 (FZD6))
Kategorien
This gene represents a member of the 'frizzled' gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting the processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis. Alternative splicing results in multiple transcript variants, some of which do not encode a protein with a predicted signal peptide.[provided by RefSeq, Aug 2011].
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Ausgewählte FZD6 Kategorien
FZD6 Antikörper
High quality antibodies with extensive validation data.
FZD6 ELISA Kits
Reliable ELISA kits for a wide range of species.
FZD6 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene FZD6 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, ELISA, IHC, IF, ICC
Validierungen
- (3)
Kat. Nr.
ABIN6258792
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Mouse, Rat
Applikation
WB, ELISA, IHC (p), ICC, IHC (fro), IF (cc), IF (p)
Validierungen
- (2)
Kat. Nr.
ABIN1713791
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
ELISA, IHC
Validierungen
- (2)
Kat. Nr.
ABIN7238471
Menge
200 μL
Datenblatt
Datenblatt
Empfohlene FZD6 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6955999
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene FZD6 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1354586
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN3092717
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN3135352
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren FZD6 Produkten
: "Functional dissection of the N-terminal extracellular domains of Frizzled 6 reveals their roles for receptor localization and Dishevelled recruitment." in: The Journal of biological chemistry, Vol. 293, Issue 46, pp. 17875-17887, (2018) (PubMed).: "A role for core planar polarity proteins in cell contact-mediated orientation of planar cell division across the mammalian embryonic skin." in: Scientific reports, Vol. 7, Issue 1, pp. 1880, (2017) (PubMed).
: "Transcriptomic analysis comparing mouse strains with extreme total lung capacities identifies novel candidate genes for pulmonary function." in: Respiratory research, Vol. 18, Issue 1, pp. 152, (2017) (PubMed).
: "Cell and Tissue Scale Forces Coregulate Fgfr2-Dependent Tetrads and Rosettes in the Mouse Embryo." in: Biophysical journal, Vol. 112, Issue 10, pp. 2209-2218, (2017) (PubMed).
: "The spatio-temporal domains of Frizzled6 action in planar polarity control of hair follicle orientation." in: Developmental biology, Vol. 409, Issue 1, pp. 181-93, (2015) (PubMed).
: "Anisotropic stress orients remodelling of mammalian limb bud ectoderm." in: Nature cell biology, Vol. 17, Issue 5, pp. 569-79, (2015) (PubMed).
: "Otitis media in sperm-associated antigen 6 (Spag6)-deficient mice." in: PLoS ONE, Vol. 9, Issue 11, pp. e112879, (2014) (PubMed).
: "Restoration of WNT4 inhibits cell growth in leukemia-derived cell lines." in: BMC cancer, Vol. 13, pp. 557, (2013) (PubMed).
: "Regulation of PCDH15 function in mechanosensory hair cells by alternative splicing of the cytoplasmic domain." in: Development (Cambridge, England), Vol. 138, Issue 8, pp. 1607-17, (2011) (PubMed).
: "Secreted Frizzled-related protein-1 is a negative regulator of androgen receptor activity in prostate cancer." in: British journal of cancer, Vol. 100, Issue 7, pp. 1165-74, (2009) (PubMed).
Synonyme und alternative Namen zu FZD6
frizzled class receptor 6 (fzd6), frizzled class receptor 6 S homeolog (fzd6.S), frizzled class receptor 6 (FZD6), frizzled class receptor 6 (Fzd6), frizzled-6, Frizzled-6, frizzled6, frz6, FZ-6, fz6, FZ6, Fz6, HFZ6, NDNC10, Xfrz6, zgc:65879, zgc:77440Bezeichner auf Proteinebene für FZD6
- frizzled-6
- frizzled homolog 6
- frizzled 6
- frizzled 6, seven transmembrane spanning receptor
- seven transmembrane helix receptor
- fz-6
- involved in Wnt signaling, encoding a Wnt receptor
- mFz6
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