FZR1 Produkte
(Fizzy/cell Division Cycle 20 Related 1 (FZR1))
Kategorien
Key regulator of ligase activity of the anaphase promoting complex/cyclosome (APC/C), which confers substrate specificity upon the complex. Associates with the APC/C in late mitosis, in replacement of CDC20, and activates the APC/C during anaphase and telophase. The APC/C remains active in degrading substrates to ensure that positive regulators of the cell cycle do not accumulate prematurely. At the G1/S transition FZR1 is phosphorylated, leading to its dissociation from the APC/C. Following DNA damage, it is required for the G2 DNA damage leads to the ubiquitination of PLK1, preventing entry into mitosis (By similarity).
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Ausgewählte FZR1 Kategorien
FZR1 Antikörper
High quality antibodies with extensive validation data.
FZR1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene FZR1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC (p), PLA
Validierungen
- (5)
Kat. Nr.
ABIN526652
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rat, Zebrafish (Danio rerio)
Applikation
WB
Validierungen
- (1)
- (5)
Kat. Nr.
ABIN2784494
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro)
Validierungen
- (3)
Kat. Nr.
ABIN1714172
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene FZR1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Validierungen
Kat. Nr.
ABIN1133421
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Validierungen
Kat. Nr.
ABIN1133422
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene FZR1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1354593
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1354595
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Tobacco (Nicotiana tabacum)
Validierungen
- (1)
Kat. Nr.
ABIN3137456
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren FZR1 Produkten
: "APC-Cdh1 Regulates Neuronal Apoptosis Through Modulating Glycolysis and Pentose-Phosphate Pathway After Oxygen-Glucose Deprivation and Reperfusion." in: Cellular and molecular neurobiology, Vol. 39, Issue 1, pp. 123-135, (2019) (PubMed).: "Hippo signaling is intrinsically regulated during cell cycle progression by APC/CCdh1." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 116, Issue 19, pp. 9423-9432, (2019) (PubMed).
: "Inhibition of neddylation causes meiotic arrest in mouse oocyte." in: Cell cycle (Georgetown, Tex.), Vol. 18, Issue 11, pp. 1254-1267, (2019) (PubMed).
: "G1/S phase progression is regulated by PLK1 degradation through the CDK1/βTrCP axis." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 31, Issue 7, pp. 2925-2936, (2017) (PubMed).
: "Aβ Induces Excitotoxicity Mediated by APC/C-Cdh1 Depletion That Can Be Prevented by Glutaminase Inhibition Promoting Neuronal Survival." in: Scientific reports, Vol. 6, pp. 31158, (2016) (PubMed).
: "Downregulation of Cdh1 signalling in spinal dorsal horn contributes to the maintenance of mechanical allodynia after nerve injury in rats." in: Molecular pain, Vol. 12, (2016) (PubMed).
: "Reduced methylation of PFKFB3 in cancer cells shunts glucose towards the pentose phosphate pathway." in: Nature communications, Vol. 5, pp. 3480, (2014) (PubMed).
Synonyme und alternative Namen zu FZR1
fizzy and cell division cycle 20 related 1 (Fzr1), fizzy/cell division cycle 20 related 1 (CDH1-C), fizzy and cell division cycle 20 related 1 (FZR1), fizzy-related protein homolog (LOC100027495), fizzy-related protein homolog (LOC100179951), fizzy/cell division cycle 20 related 1 (Drosophila) (Fzr1), fizzy/cell division cycle 20 related 1a (fzr1a), AW108046, CDC20C, CDH1, Cdh1, CDH1-C, FYR, Fyr, FZR, fzr1, FZR2, HCDH, HCDH1, zgc:55450Bezeichner auf Proteinebene für FZR1
- fizzy-related protein homolog
- fizzy/cell division cycle 20 related 1 (Drosophila)
- fizzy-related protein FZR
- Fizzy-related protein-like protein
- fizzy/cell division cycle 20 related 1
- CDC20-like 1b
- CDC20-like protein 1
- cdh1/Hct1 homolog
- cell division cycle 20 related 1
Haben Sie etwas anderes gesucht?
- FZD9
- FZD7
- FZD6
- FZD5
- FZD4
- FZD3
- FZD2
- FZD1
- Fyv7p
- FYV10
- FYTTD1
- FYN
- FYCO1
- FYB1
- FYB
- FXYD7
- FXYD6P3
- FXYD6
- FXYD5
- FXYD4
- G Antigen 1
- G Antigen 10
- G Antigen 12B
- G Antigen 12F
- G Antigen 12G
- G Antigen 12H
- G Antigen 12I
- G Antigen 12J
- G Antigen 13
- G Antigen 2A
- G Antigen 2C
- G Antigen 2D
- G Antigen 4
- G Antigen 5
- G Antigen 7
- G Kinase Anchoring Protein 1
- G Protein-Coupled Receptor 1
- G Protein-Coupled Receptor 110
- G Protein-Coupled Receptor 115
- G Protein-Coupled Receptor 116
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