GZMA Antikörper (AA 29-260)

Produktnummer ABIN7177245

Produktdetails anti-GZMA Antikörper

Target: GZMA (Granzyme A (Granzyme 1, Cytotoxic T-Lymphocyte-Associated serine Esterase 3) (GZMA))

Bindungsspezifität: AA 29-260

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GZMA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Kreuzreaktivität: Human, Maus

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Mouse Granzyme A protein (29-260AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:5000,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu GZMA

Target: GZMA (Granzyme A (Granzyme 1, Cytotoxic T-Lymphocyte-Associated serine Esterase 3) (GZMA))

Andere Bezeichnung: Gzma (GZMA Produkte)

Synonyme: gzmA antikoerper, GZMA antikoerper, AW494114 antikoerper, Ctla-3 antikoerper, Ctla3 antikoerper, Hf antikoerper, SE1 antikoerper, TSP-1 antikoerper, TSP1 antikoerper, CTLA3 antikoerper, HFSP antikoerper, granzyme A antikoerper, Granzyme A antikoerper, granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) antikoerper, gzmA antikoerper, GZMA antikoerper, graa antikoerper, Gzma antikoerper

Hintergrund:

Background: Abundant protease in the cytosolic granules of cytotoxic T-cells and NK-cells which activates caspase-independent cell death with morphological features of apoptosis when delivered into the target cell through the immunological synapse. It cleaves after Lys or Arg. Cleaves APEX1 after \\\'Lys-31\\\' and destroys its oxidative repair activity. Cleaves the nucleosome assembly protein SET after \\\'Lys-189\\\', which disrupts its nucleosome assembly activity and allows the SET complex to translocate into the nucleus to nick and degrade the DNA (By similarity).

Aliases: Gzma antibody, Ctla-3 antibody, Ctla3 antibody, Mtsp-1 antibody, Granzyme A antibody, EC 3.4.21.78 antibody, Autocrine thymic lymphoma granzyme-like serine protease antibody, CTLA-3 antibody, Fragmentin-1 antibody, T cell-specific serine protease 1 antibody, TSP-1 antibody

UniProt: P11032

Pathways: Apoptose