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GZMA Produkte

(Granzyme A (Granzyme 1, Cytotoxic T-Lymphocyte-Associated serine Esterase 3) (GZMA))

Kategorien

Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here is a T cell- and natural killer cell-specific serine protease that may function as a common component necessary for lysis of target cells by cytotoxic T lymphocytes and natural killer cells. [provided by RefSeq, Jul 2008].

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Ausgewählte GZMA Kategorien

GZMA Antikörper

High quality antibodies with extensive validation data.

GZMA ELISA Kits

Reliable ELISA kits for a wide range of species.

GZMA Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene GZMA Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC, IP, ICC
Validierungen
  • (2)
Kat. Nr. ABIN7440233
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation IP, FACS, ICC
Validierungen
  • (2)
Kat. Nr. ABIN7505978
Menge 0.1 mg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IF
Validierungen
  • (2)
Kat. Nr. ABIN6141551
Menge 100 μL
Datenblatt Datenblatt

Empfohlene GZMA ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (2)
  • (1)
Kat. Nr. ABIN6956296
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6956297
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6999395
Menge 96 tests
Datenblatt Datenblatt

Empfohlene GZMA Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7123196
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1306259
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1306257
Menge 10 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren GZMA Produkten

Spacek, Musilova, Andrys, Soucek, Burckova, Pavlicek, Pliskova, Bolehovska, Kacerovsky: "Extracellular granzyme A in amniotic fluid is elevated in the presence of sterile intra-amniotic inflammation in preterm prelabor rupture of membranes." in: The journal of maternal-fetal & neonatal medicine, pp. 1-10, (2020) (PubMed).

Tang, Zha, Guo, Shi, Xu: "CXCR5+CD8+ T cells present elevated capacity in mediating cytotoxicity toward autologous tumor cells through interleukin 10 in diffuse large B-cell lymphoma." in: International immunopharmacology, Vol. 50, pp. 146-151, (2018) (PubMed).

Ma, Huang, Zhang, Wang, Chen: "Exposure to particulate matter 2.5 (PM2.5) induced macrophage-dependent inflammation, characterized by increased Th1/Th17 cytokine secretion and cytotoxicity." in: International immunopharmacology, Vol. 50, pp. 139-145, (2018) (PubMed).

Qiu, Hu, Gao, Chen, Chen, Yuan, Huang, Xu, Yang: "Interleukin 10 enhanced CD8+ T cell activity and reduced CD8+ T cell apoptosis in patients with diffuse large B cell lymphoma." in: Experimental cell research, Vol. 360, Issue 2, pp. 146-152, (2017) (PubMed).

Kamata, Kimura, Matsuda, Tengara, Kamo, Umehara, Iizumi, Kawasaki, Suga, Ogawa, Tominaga, Takamori: "Relationships among plasma granzyme B level, pruritus and dermatitis in patients with atopic dermatitis." in: Journal of dermatological science, Vol. 84, Issue 3, pp. 266-271, (2016) (PubMed).

Kurioka, Ussher, Cosgrove, Clough, Fergusson, Smith, Kang, Walker, Hansen, Willberg, Klenerman: "MAIT cells are licensed through granzyme exchange to kill bacterially sensitized targets." in: Mucosal immunology, Vol. 8, Issue 2, pp. 429-40, (2015) (PubMed).

Hildebrand, Bode, Rieß, Cerny, Waldhuber, Römmler, Strack, Korten, Orth, Miethke, Heeg, Kubatzky: "Granzyme A produces bioactive IL-1? through a nonapoptotic inflammasome-independent pathway." in: Cell reports, Vol. 9, Issue 3, pp. 910-7, (2014) (PubMed).

Herth, Witzens-Harig, Beckhove, Hose, Meissner, Neuber, Engelhardt, Haas, Neben, Ho, Klein, Goldschmidt, Hundemer: "Thalidomide maintenance therapy maturates the T cell compartment and compromises antigen-specific antitumor immunity in patients with multiple myeloma." in: Experimental hematology, Vol. 41, Issue 3, pp. 231-40, (2013) (PubMed).

Kreft, Verbraak, Wierenga-Wolf, van Meurs, Oostra, Laman, Hintzen: "The IL-7Rα pathway is quantitatively and functionally altered in CD8 T cells in multiple sclerosis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 188, Issue 4, pp. 1874-83, (2012) (PubMed).

Meade, Wilson, Holmes, de Wynter, Brett, Straszynski, Ballard, Trapani, McDermott, Cook: "Proteolytic activation of the cytotoxic phenotype during human NK cell development." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 183, Issue 2, pp. 803-13, (2009) (PubMed).

Synonyme und alternative Namen zu GZMA

granzyme A (gzmA), granzyme A (GZMA), Granzyme A (graa), granzyme A (Gzma), granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) (GZMA), AW494114, Ctla-3, Ctla3, CTLA3, gzmA, GZMA, Hf, HFSP, SE1, TSP-1, TSP1

Bezeichner auf Proteinebene für GZMA

  • granzyme A
  • Granzyme A
  • BLT esterase
  • H factor
  • Hanukah factor
  • autocrine thymic lymphoma granzyme-like serine protease
  • fragmentin-1
  • serine esterase 1
  • t cell-specific serine protease 1
  • CTL tryptase
  • Granzyme A (Cytotoxic T-lymphocyte-associated serine esterase-3; Hanukah factor serine protease)
  • HF
  • cytotoxic T-lymphocyte proteinase 1
  • h factor
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