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GZMB Produkte

(Granzyme B (GZMB))

Kategorien

Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein encoded by this gene is crucial for the rapid induction of target cell apoptosis by CTL in cell-mediated immune response. [provided by RefSeq, Jul 2008].

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Ausgewählte GZMB Kategorien

GZMB Antikörper

High quality antibodies with extensive validation data.

GZMB ELISA Kits

Reliable ELISA kits for a wide range of species.

GZMB Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene GZMB Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC, IP, ICC
Validierungen
  • (7)
Kat. Nr. ABIN7432145
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, StM
Validierungen
  • (5)
Kat. Nr. ABIN6939591
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human, Non-Human Primate
Applikation FACS
Validierungen
  • (3)
  • (3)
Kat. Nr. ABIN1302451
Menge 0.1 mg
Datenblatt Datenblatt

Empfohlene GZMB ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN6956298
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN6956299
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN6956300
Menge 96 tests
Datenblatt Datenblatt

Empfohlene GZMB Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1306262
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1306264
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Mouse
Source Human Cells
Validierungen
  • (1)
Kat. Nr. ABIN7320540
Menge 50 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren GZMB Produkten

Islimye Taskin, Guney, Adali, Hismiogullari, Dodurga, Elmas: "Granzyme B levels and granzyme B polymorphisms in peripheral blood of patients with endometriosis: a preliminary study." in: Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology, Vol. 41, Issue 1, pp. 94-99, (2021) (PubMed).

Qian, Shi, Qi, Zhao, Huang, Han, Zhou, Liu, Liu, Lu, Yuan, Zhao, Kang: "A novel Granzyme B nanoparticle delivery system simulates immune cell functions for suppression of solid tumors." in: Theranostics, Vol. 9, Issue 25, pp. 7616-7627, (2020) (PubMed).

Baumann, Dunkel, Schmid, Schmitt, Hiltensperger, Lohr, Laketa, Donakonda, Ahting, Lorenz-Depiereux, Heil, Schredelseker, Simeoni, Fecher, Körber, Bauer, Hüser, Hartmann, Laschinger, Eyerich, Eyerich et al.: "Regulatory myeloid cells paralyze T cells through cell-cell transfer of the metabolite methylglyoxal. ..." in: Nature immunology, Vol. 21, Issue 5, pp. 555-566, (2020) (PubMed).

Bengsch, Ohtani, Khan, Setty, Manne, OBrien, Gherardini, Herati, Huang, Chang, Newell, Bovenschen, Peer, Albelda, Wherry: "Epigenomic-Guided Mass Cytometry Profiling Reveals Disease-Specific Features of Exhausted CD8 T Cells." in: Immunity, Vol. 48, Issue 5, pp. 1029-1045.e5, (2019) (PubMed).

Park, Shin, Kim, Bilsborrow, Mohanty, Montgomery, Shaw, You, Kang: "Transcriptomic analysis of human IL-7 receptor alpha low and high effector memory CD8+ T cells reveals an age-associated signature linked to influenza vaccine response in older adults." in: Aging cell, Vol. 18, Issue 4, pp. e12960, (2019) (PubMed).

Paidipally, Tripathi, Van, Radhakrishnan, Dhiman, Venkatasubramanian, Devalraju, Tvinnereim, Valluri, Vankayalapati: "Interleukin-21 Regulates Natural Killer Cell Responses During Mycobacterium tuberculosis Infection." in: The Journal of infectious diseases, Vol. 217, Issue 8, pp. 1323-1333, (2019) (PubMed).

Giles, Hao, Padget, Song, Zhang, Lynes, Sanchez, Liu, Jung, Cao, Fujii, Jensen, Gillespie, Schlom, Gilbert, Nduom, Yang, Lee, Soon-Shiong, Hodge, Park: "Efficient ADCC killing of meningioma by avelumab and a high-affinity natural killer cell line, haNK." in: JCI insight, Vol. 4, Issue 20, (2019) (PubMed).

Ouni, Gharsalli, Dirix, Braiek, Sendi, Jarraya, Douik El Gharbi, Barbouche, Benabdessalem: "Granzyme B induced by Rv0140 antigen discriminates latently infected from active tuberculosis individuals." in: Journal of leukocyte biology, Vol. 105, Issue 2, pp. 297-306, (2019) (PubMed).

Gatault, Al-Hajj, Noble, Chevallier, Piollet, Forconi, Gaudy-Graffin, Thibault, Miquelestorena-Standley, Halimi, Büchler, Lemoine, Baron: "CMV-infected kidney grafts drive the expansion of blood-borne CMV-specific T cells restricted by shared class I HLA molecules via presentation on donor cells." in: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, Vol. 18, Issue 8, pp. 1904-1913, (2019) (PubMed).

Hartana, Ahlén Bergman, Zirakzadeh, Krantz, Winerdal, Winerdal, Johansson, Alamdari, Jakubczyk, Glise, Riklund, Sherif, Winqvist: "Urothelial bladder cancer may suppress perforin expression in CD8+ T cells by an ICAM-1/TGFβ2 mediated pathway." in: PLoS ONE, Vol. 13, Issue 7, pp. e0200079, (2019) (PubMed).

Synonyme und alternative Namen zu GZMB

granzyme B (GZMB), CCPI, CGL-1, CGL1, CSP-B, CSPB, CTLA1, CTSGL1, HLP, SECT

Bezeichner auf Proteinebene für GZMB

  • C11
  • CTLA-1
  • T-cell serine protease 1-3E
  • cathepsin G-like 1
  • cytotoxic T-lymphocyte proteinase 2
  • cytotoxic serine protease B
  • fragmentin 2
  • fragmentin-2
  • granzyme B
  • human lymphocyte protein
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