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Rekombinanter GZMB Antikörper (AA 19-247)

GZMB Reaktivität: Human WB, IHC, ICC, IF (p), mIF Wirt: Kaninchen Monoclonal BLR022E unconjugated Recombinant Antibody
Produktnummer ABIN7449554
  • Target Alle GZMB Antikörper anzeigen
    GZMB (Granzyme B (GZMB))
    Antikörpertyp
    Recombinant Antibody
    Bindungsspezifität
    • 19
    • 16
    • 13
    • 9
    • 9
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 19-247
    Reaktivität
    • 122
    • 53
    • 25
    • 10
    • 4
    • 2
    • 1
    • 1
    Human
    Wirt
    • 77
    • 48
    • 2
    Kaninchen
    Klonalität
    • 76
    • 51
    Monoklonal
    Konjugat
    • 78
    • 11
    • 8
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser GZMB Antikörper ist unkonjugiert
    Applikation
    • 71
    • 41
    • 40
    • 37
    • 17
    • 17
    • 17
    • 13
    • 13
    • 9
    • 8
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Multiplex Immunofluorescence (mIF)
    Verwendungszweck
    Rabbit anti-Granzyme B Recombinant Monoclonal Antibody [BLR022E]
    Immunogen
    residues 19-247 (mature protein)
    Klon
    BLR022E
    Isotyp
    IgG
    Top Product
    Discover our top product GZMB Primärantikörper
  • Applikationshinweise

    IHC-IF: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    ICC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.

    WB: 17:40:00

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    50 μg/mL
    Buffer
    Borate Buffered Saline (BBS) pH 8.2 with 0.1 % BSA and 0.09 % Sodium Azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Haltbarkeit
    12 months
  • Target
    GZMB (Granzyme B (GZMB))
    Andere Bezeichnung
    Granzyme B (GZMB Produkte)
    Synonyme
    CCPI antikoerper, CGL-1 antikoerper, CGL1 antikoerper, CSP-B antikoerper, CSPB antikoerper, CTLA1 antikoerper, CTSGL1 antikoerper, HLP antikoerper, SECT antikoerper, granzyme B antikoerper, GZMB antikoerper
    Hintergrund
    Background: Granzyme B is a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing [taken from NCBI Entrez Gene (Gene ID: 3002)]
    Gen-ID
    3002
    NCBI Accession
    NP_004122
    UniProt
    P10144
    Pathways
    Apoptose, Caspase Kaskade in der Apoptose
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