PPP2CA Antikörper (Catalytic Subunit alpha) (Biotin)

Produktnummer ABIN7347868

Produktdetails anti-PPP2CA Antikörper (Biotin)

Target: PPP2CA (Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme (PPP2CA))

Bindungsspezifität: AA 1-309, Catalytic Subunit alpha

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPP2CA Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform protein (1-309AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu PPP2CA

Target: PPP2CA (Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme (PPP2CA))

Andere Bezeichnung: PPP2CA (PPP2CA Produkte)

Synonyme: PP2Ac antikoerper, PP2CA antikoerper, PP2Calpha antikoerper, RP-C antikoerper, PP2A antikoerper, R75353 antikoerper, Pp2a1 antikoerper, pp2ac antikoerper, zgc:110641 antikoerper, protein phosphatase 2 catalytic subunit alpha antikoerper, protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform antikoerper, protein phosphatase 2, catalytic subunit, alpha isozyme antikoerper, protein phosphatase 2 catalytic subunit alpha L homeolog antikoerper, protein phosphatase 2, catalytic subunit, beta isozyme antikoerper, serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform antikoerper, PPP2CA antikoerper, Ppp2ca antikoerper, ppp2ca.L antikoerper, ppp2cb antikoerper, LOC471633 antikoerper, ppp2ca antikoerper

Hintergrund:

Background: PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGOL2 to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I. Can dephosphorylate SV40 large T antigen and p53/TP53. Activates RAF1 by dephosphorylating it at 'Ser-259'.

Aliases: PP2A A antibody, PP2A alpha antibody, PP2A B antibody, PP2A beta antibody, PP2A-alpha antibody, PP2A-beta antibody, PP2AA_HUMAN antibody, PP2Aalpha antibody, PP2AB_HUMAN antibody, PP2Abeta antibody, PP2Ac antibody, PP2CA antibody, PP2Calpha antibody, PP2CB antibody, PPP2CA antibody, PPP2CB antibody, Protein phosphatase 2 catalytic subunit alpha isoform antibody, Protein phosphatase 2 catalytic subunit beta isoform antibody, Protein phosphatase type 2A catalytic subunit antibody, Replication protein C antibody, RP C antibody, RP-C antibody, RPC antibody, Serine/threonine protein phosphatase 2A catalytic subunit alpha isoform antibody, Serine/threonine protein phosphatase 2A catalytic subunit beta isoform antibody, Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform antibody

UniProt: P67775

Pathways: PI3K-Akt Signalweg, Mitotic G1-G1/S Phases, Hepatitis C, Toll-Like Receptors Cascades