PPP2CA Antikörper (C-Term)

Produktnummer ABIN2856333

Produktdetails anti-PPP2CA Antikörper

Target: PPP2CA (Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme (PPP2CA))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPP2CA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Kreuzreaktivität: Ratte (Rattus), Zebrafisch (Danio rerio), Xenopus laevis, Xenopus tropicalis, Hund, Schwein, Kaninchen, Huhn, Rind (Kuh)

Kreuzreaktivität (Details): Rat (100 %), Zebrafish (100 %), Xenopus laevis (100 %), Xenopus Tropicalis (100 %), Dog (100 %), Pig (100 %), Rabbit (100 %), Chicken (100 %), Bovine (100 %)

Produktmerkmale: Rabbit Polyclonal antibody to PP2A alpha (protein phosphatase 2, catalytic subunit, alpha isozyme)
PP2A alpha antibody

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human PP2A alpha. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Immunoprecipitation 1:100-1:500* Western blot 1:1000-1:10000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Immunoprecipitation1:100-1:500* Western blot1:1000-1:10000*

Kommentare:

Positive Control: 293T , A431 , H1299 , HeLaS3 , Molt-4 , Raji , mouse brain

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.479 mg/mL

Buffer: 1XPBS, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu PPP2CA

Target: PPP2CA (Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme (PPP2CA))

Andere Bezeichnung: PP2A alpha (PPP2CA Produkte)

Synonyme: PP2Ac antikoerper, PP2CA antikoerper, PP2Calpha antikoerper, RP-C antikoerper, PP2A antikoerper, R75353 antikoerper, Pp2a1 antikoerper, pp2ac antikoerper, zgc:110641 antikoerper, protein phosphatase 2 catalytic subunit alpha antikoerper, protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform antikoerper, protein phosphatase 2, catalytic subunit, alpha isozyme antikoerper, protein phosphatase 2 catalytic subunit alpha L homeolog antikoerper, protein phosphatase 2, catalytic subunit, beta isozyme antikoerper, serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform antikoerper, PPP2CA antikoerper, Ppp2ca antikoerper, ppp2ca.L antikoerper, ppp2cb antikoerper, LOC471633 antikoerper, ppp2ca antikoerper

Hintergrund: This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes an alpha isoform of the catalytic subunit.

Cellular Localization: Cytoplasm , Nucleus , Centromere , Spindle

Molekulargewicht: 36 kDa

Gen-ID: 5515

Pathways: PI3K-Akt Signalweg, Mitotic G1-G1/S Phases, Hepatitis C, Toll-Like Receptors Cascades