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Rekombinanter C-JUN Antikörper (pSer63)

Name: Rekombinanter C-JUN Antikörper (pSer63)
Brand: antibodies-online
SKU: ABIN7127704
Price: 385 EUR
Availability: InStock

JUN Reaktivität: Human WB, IHC, ELISA, IF Wirt: Kaninchen Monoclonal 4A11 unconjugated Recombinant Antibody

Western Blot Positive WB detected in: Hela whole cell lysate, A549 whole cell lysate(treated with Calyculin A or EGF) All lanes: Phospho-JUN antibody at 0. (Rekombinanter C-JUN Antikörper (pSer63))

Immunofluorescence staining of A549 cells with ABIN7127704 at 1:100,counter-stained with DAPI. (Rekombinanter C-JUN Antikörper (pSer63))

IHC image of ABIN7127704 diluted at 1:100 and staining in paraffin-embedded human breast cancer performed on a Leica BondTM system. (Rekombinanter C-JUN Antikörper (pSer63))

IHC

3 Abbildungen

Produktnummer ABIN7127704

Datenblatt (PDF)

Target Alle C-JUN (JUN) Antikörper anzeigen

C-JUN (JUN) (Jun Proto-Oncogene (JUN))

Antikörpertyp

Recombinant Antibody
Bindungsspezifität
42

41

30

29

22

16

16

15

10

9

8

8

7

7

7

7

7

6

6

6

5

5

4

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1
pSer63
Reaktivität
369

208

191

34

28

21

19

17

16

12

12

7

5

4

3

1

1
Human
Wirt
360

17

2
Kaninchen
Passende Sekundärantikörper
Klonalität
336

43
Monoklonal
Konjugat
189

23

16

16

16

15

15

15

14

13

12

6

5

5

5

5

5

2

1

1
Dieser C-JUN Antikörper ist unkonjugiert
Applikation
259

124

120

89

57

46

43

43

42

23

11

9

7

4

3

2

2

2

1

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Kreuzreaktivität

Human

Aufreinigung

Affinity-chromatography

Immunogen

A synthesized peptide derived from human Phospho-JUN (S63)

Klon

4A11

Isotyp

IgG

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Applikationshinweise

Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200, IF:1:20-1:200,

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

-20 °C,-80 °C

Informationen zur Lagerung

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target

C-JUN (JUN) (Jun Proto-Oncogene (JUN))

Andere Bezeichnung

JUN (JUN Produkte)

Synonyme

AP-1 antikoerper, AP1 antikoerper, c-Jun antikoerper, fj36h07 antikoerper, wu:fj36h07 antikoerper, zgc:65863 antikoerper, Junc antikoerper, c-jun antikoerper, CG2275 antikoerper, D-Jun antikoerper, D-jun antikoerper, D-jun/Jra antikoerper, DJUN antikoerper, DJun antikoerper, Djun antikoerper, Dmel\\CG2275 antikoerper, JRA antikoerper, JUN antikoerper, Jun antikoerper, V antikoerper, cJun antikoerper, d-JRA antikoerper, d-Jun antikoerper, d-jun antikoerper, dAP-1 antikoerper, dJRA antikoerper, dJUN antikoerper, dJra antikoerper, dJun antikoerper, djun antikoerper, dm-Jun antikoerper, jra antikoerper, jun antikoerper, l(2)46Ef antikoerper, l(2)IA109 antikoerper, l(2R)IA109 antikoerper, Jun proto-oncogene, AP-1 transcription factor subunit antikoerper, jun proto-oncogene S homeolog antikoerper, jun proto-oncogene antikoerper, Jun-related antigen antikoerper, jun proto-oncogene L homeolog antikoerper, JUN antikoerper, Jun antikoerper, jun.S antikoerper, jun antikoerper, Jra antikoerper, jun.L antikoerper

Hintergrund

Background: Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells (PubMed:24623306). Binds to the USP28 promoter in colorectal cancer (CRC) cells (PubMed:24623306).
Aliases: Transcription factor AP-1, Activator protein 1, AP1, Proto-oncogene c-Jun, V-jun avian sarcoma virus 17 oncogene homolog, p39, JUN

UniProt

P05412

Pathways

MAPK Signalweg, RTK Signalweg, WNT Signalweg, Fc-epsilon Rezeptor Signalübertragung, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Autophagie, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling, S100 Proteine