LAMTOR1 Antikörper

Produktnummer ABIN7074464

Produktdetails anti-LAMTOR1 Antikörper

Target: LAMTOR1 (Late Endosomal/lysosomal Adaptor, MAPK and mTOR Activator 1 (LAMTOR1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LAMTOR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Human, Ratte

Aufreinigung: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse LAMTOR1

Anwendungsinformationen

Applikationshinweise: WB (H,M,R) 1: 500-1: 1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu LAMTOR1

Target: LAMTOR1 (Late Endosomal/lysosomal Adaptor, MAPK and mTOR Activator 1 (LAMTOR1))

Andere Bezeichnung: LAMTOR1 (LAMTOR1 Produkte)

Synonyme: C11orf59 antikoerper, PDRO antikoerper, Ragulator1 antikoerper, p18 antikoerper, p27RF-Rho antikoerper, 2400001E08Rik antikoerper, Pdro antikoerper, C15H11orf59 antikoerper, c11orf59 antikoerper, flj20625 antikoerper, p27rf-rho antikoerper, pdro antikoerper, ragulator1 antikoerper, late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 antikoerper, late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 S homeolog antikoerper, LAMTOR1 antikoerper, Lamtor1 antikoerper, lamtor1.S antikoerper

Hintergrund: Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, recruits the Rag GTPases and the mTORC1 complex to lysosomes, a key step in activation of the TOR signaling cascade by amino acids. Directly responsible for anchoring the Ragulator complex to membranes. Also required for late endosomes/lysosomes biogenesis it may regulate both the recycling of receptors through endosomes and the MAPK signaling pathway through recruitment of some of its components to late endosomes. May be involved in cholesterol homeostasis regulating LDL uptake and cholesterol release from late endosomes/lysosomes. May also play a role in RHOA activation.

Molekulargewicht: 18 kDa

Gen-ID: 66508

NCBI Accession: NP_079881

UniProt: Q9CQ22