LAMTOR1 Antikörper (N-Term)

Produktnummer ABIN6991973

Produktdetails anti-LAMTOR1 Antikörper

Target: LAMTOR1 (Late Endosomal/lysosomal Adaptor, MAPK and mTOR Activator 1 (LAMTOR1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LAMTOR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: LAMTOR1 antibody is human, mouse and rat specific. LAMTOR1 antibody is predicted to not cross-react with other LAMTOR family proteins.

Aufreinigung: LAMTOR1 antibody is affinity chromatography purified via peptide column.

Immunogen: Rabbit polyclonal LAMTOR1 antibody was raised against a 17 amino acid peptide near the amino terminus of human LAMTOR1 . The immunogen is located within the first 50 amino acids of LAMTOR1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: LAMTOR1 antibody can be used for detection of LAMTOR1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: LAMTOR1 antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: LAMTOR1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu LAMTOR1

Target: LAMTOR1 (Late Endosomal/lysosomal Adaptor, MAPK and mTOR Activator 1 (LAMTOR1))

Andere Bezeichnung: LAMTOR1 (LAMTOR1 Produkte)

Synonyme: C11orf59 antikoerper, PDRO antikoerper, Ragulator1 antikoerper, p18 antikoerper, p27RF-Rho antikoerper, 2400001E08Rik antikoerper, Pdro antikoerper, C15H11orf59 antikoerper, c11orf59 antikoerper, flj20625 antikoerper, p27rf-rho antikoerper, pdro antikoerper, ragulator1 antikoerper, late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 antikoerper, late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 S homeolog antikoerper, LAMTOR1 antikoerper, Lamtor1 antikoerper, lamtor1.S antikoerper

Hintergrund: LAMTOR1 is a 161 amino acid membrane protein belonging to the LAMTOR family. It has been identified to interact with and recruit the four Rag GTPases (Rag A-D) to the surface of lysosomes (1). The mTORC1 kinase complex is a critical component in the regulation of cell growth (2). As part of the ragulator complex, LAMTOR1 recruits the Rag GTPases and the mTORC1 complex to lysosomes, a key step in activation of the TOR signaling cascade by amino acids (3). LAMTOR1 may be involved in cholesterol homeostasis regulating LDL uptake and cholesterol release from late endosomes / lysosomes (4).

Molekulargewicht: Predicted: 18 kDa

Observed: 18 kDa

Gen-ID: 55004

NCBI Accession: NP_060377

UniProt: Q6IAA8