Dystrophin Antikörper

Produktnummer ABIN7073791

Produktdetails anti-Dystrophin Antikörper

Target: Dystrophin (DMD)

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Dystrophin Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität: Ratte

Aufreinigung: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse Dystrophin

Anwendungsinformationen

Applikationshinweise: IHC/IF (M,R) 1:600-1:1200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu Dystrophin

Target: Dystrophin (DMD)

Andere Bezeichnung: Dystrophin (DMD Produkte)

Synonyme: DMD antikoerper, Dmd antikoerper, MGC83347 antikoerper, DKFZp459C1629 antikoerper, dmd antikoerper, MGC79631 antikoerper, DKFZp468A1620 antikoerper, Dp71 antikoerper, cb664 antikoerper, zfDYS antikoerper, im:6911785 antikoerper, zgc:110165 antikoerper, BMD antikoerper, CMD3B antikoerper, DXS142 antikoerper, DXS164 antikoerper, DXS206 antikoerper, DXS230 antikoerper, DXS239 antikoerper, DXS268 antikoerper, DXS269 antikoerper, DXS270 antikoerper, DXS272 antikoerper, DXSmh7 antikoerper, DXSmh9 antikoerper, Dp427 antikoerper, dys antikoerper, mdx antikoerper, pke antikoerper, DNADMD1 antikoerper, RATDMD antikoerper, CG17750 antikoerper, CG31175 antikoerper, CG34157 antikoerper, CG7240 antikoerper, CG7243 antikoerper, CG7344 antikoerper, DLP antikoerper, DLP1 antikoerper, DLP186 antikoerper, DLP2 antikoerper, DLP3 antikoerper, DmDLP antikoerper, DmDYS antikoerper, Dmel\\CG34157 antikoerper, Dp117 antikoerper, Dp186 antikoerper, Dp205 antikoerper, GI3046716 antikoerper, IDLP antikoerper, det antikoerper, dmDLP antikoerper, dmDp186 antikoerper, dmDys antikoerper, dystrophin antikoerper, dystrophin, gene 1 L homeolog antikoerper, dystrophin, gene 1 antikoerper, dystrophin, muscular dystrophy antikoerper, Dystrophin antikoerper, DMD antikoerper, LOC708073 antikoerper, dmd.1.L antikoerper, LOC465557 antikoerper, dmd.1 antikoerper, dmd antikoerper, Dmd antikoerper, Dys antikoerper

Hintergrund: Dystrophin (DMD or BMD) is a large muscle protein whose mutations cause Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD), the childhood neuromuscular disorders that result in progressive muscle weakness, respiratory difficulties and cardiovascular dysfunction. Dystrophin is a crucial component of the dystrophin-glycoprotein complex which is essential for muscle membrane integrity and stability. Dystrophin is located on the cytoplasmic face of the sarcolemma and connects the cytoskeletal network to the sarcolemma and extracellular matrix. Multiple isoforms of dystrophin exist due to the alternative splicing, with a wide range of MW (69-72, 110-143, 271, 426 kDa). Most tissues contain transcripts of several isoforms.

Gen-ID: 13405

NCBI Accession: NP_031894

UniProt: P11531

Pathways: Skeletal Muscle Fiber Development