Dystrophin Antikörper

Produktnummer ABIN7008615

Produktdetails anti-Dystrophin Antikörper

Target: Dystrophin (DMD)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Dystrophin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human DMD (NP_004007.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:200-1:2000 IHC 1:50-1:200 IF 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Dystrophin

Target: Dystrophin (DMD)

Andere Bezeichnung: DMD (DMD Produkte)

Synonyme: DMD antikoerper, Dmd antikoerper, MGC83347 antikoerper, DKFZp459C1629 antikoerper, dmd antikoerper, MGC79631 antikoerper, DKFZp468A1620 antikoerper, Dp71 antikoerper, cb664 antikoerper, zfDYS antikoerper, im:6911785 antikoerper, zgc:110165 antikoerper, BMD antikoerper, CMD3B antikoerper, DXS142 antikoerper, DXS164 antikoerper, DXS206 antikoerper, DXS230 antikoerper, DXS239 antikoerper, DXS268 antikoerper, DXS269 antikoerper, DXS270 antikoerper, DXS272 antikoerper, DXSmh7 antikoerper, DXSmh9 antikoerper, Dp427 antikoerper, dys antikoerper, mdx antikoerper, pke antikoerper, DNADMD1 antikoerper, RATDMD antikoerper, CG17750 antikoerper, CG31175 antikoerper, CG34157 antikoerper, CG7240 antikoerper, CG7243 antikoerper, CG7344 antikoerper, DLP antikoerper, DLP1 antikoerper, DLP186 antikoerper, DLP2 antikoerper, DLP3 antikoerper, DmDLP antikoerper, DmDYS antikoerper, Dmel\\CG34157 antikoerper, Dp117 antikoerper, Dp186 antikoerper, Dp205 antikoerper, GI3046716 antikoerper, IDLP antikoerper, det antikoerper, dmDLP antikoerper, dmDp186 antikoerper, dmDys antikoerper, dystrophin antikoerper, dystrophin, gene 1 L homeolog antikoerper, dystrophin, gene 1 antikoerper, dystrophin, muscular dystrophy antikoerper, Dystrophin antikoerper, DMD antikoerper, LOC708073 antikoerper, dmd.1.L antikoerper, LOC465557 antikoerper, dmd.1 antikoerper, dmd antikoerper, Dmd antikoerper, Dys antikoerper

Hintergrund: This gene spans a genomic range of greater than 2 Mb and encodes a large protein containing an N-terminal actin-binding domain and multiple spectrin repeats. The encoded protein forms a component of the dystrophin-glycoprotein complex (DGC), which bridges the inner cytoskeleton and the extracellular matrix. Deletions, duplications, and point mutations at this gene locus may cause Duchenne muscular dystrophy (DMD), Becker muscular dystrophy (BMD), or cardiomyopathy. Alternative promoter usage and alternative splicing result in numerous distinct transcript variants and protein isoforms for this gene.

Molekulargewicht:

Observed_MW: 427 kDa

Calculated_MW: 57-72 kDa/271 kDa/425-426 kDa

Gen-ID: 1756

UniProt: P11532

Pathways: Skeletal Muscle Fiber Development