FBXO11 Antikörper

Produktnummer ABIN7261998

Produktdetails anti-FBXO11 Antikörper

Target: FBXO11 (F-Box Protein 11 (FBXO11))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FBXO11 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human FBXO11 (NP_001177203.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000 IF 1:20-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu FBXO11

Target: FBXO11 (F-Box Protein 11 (FBXO11))

Andere Bezeichnung: FBXO11 (FBXO11 Produkte)

Synonyme: FBX11 antikoerper, PRMT9 antikoerper, UBR6 antikoerper, VIT1 antikoerper, C80048 antikoerper, Jf antikoerper, Vit1 antikoerper, fbxo11 antikoerper, MGC84634 antikoerper, FBXO11 antikoerper, im:6906507 antikoerper, wu:fj83f06 antikoerper, zgc:153171 antikoerper, Fbxo11 antikoerper, DKFZp459P2410 antikoerper, F-box protein 11 antikoerper, F-box protein 11 L homeolog antikoerper, F-box protein 11a antikoerper, F-box only protein 11 antikoerper, hypothetical protein antikoerper, FBXO11 antikoerper, Fbxo11 antikoerper, fbxo11.L antikoerper, fbxo11a antikoerper, CpipJ_CPIJ009919 antikoerper, CpipJ_CPIJ017549 antikoerper, Bm1_52225 antikoerper, LOAG_16571 antikoerper, fbxo11 antikoerper, LOC100115478 antikoerper

Hintergrund: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It can function as an arginine methyltransferase that symmetrically dimethylates arginine residues, and it acts as an adaptor protein to mediate the neddylation of p53, which leads to the suppression of p53 function. This gene is known to be down-regulated in melanocytes from patients with vitiligo, a skin disorder that results in depigmentation. Polymorphisms in this gene are associated with chronic otitis media with effusion and recurrent otitis media (COME/ROM), a hearing loss disorder, and the knockout of the homologous mouse gene results in the deaf mouse mutant Jeff (Jf), a single gene model of otitis media. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.

Molekulargewicht:

Observed_MW: 130 kDa

Calculated_MW: 23 kDa/62 kDa/65 kDa/94 kDa/103 kDa/106 kDa

Gen-ID: 80204

UniProt: Q86XK2

Pathways: Sensory Perception of Sound