F-Box Protein 11 (FBXO11) (Middle Region) Antikörper

Details zu Produkt Nr. ABIN2774788, Anbieter: Anmelden zum Anzeigen
Antigen
  • FBX11
  • PRMT9
  • UBR6
  • VIT1
  • C80048
  • Jf
  • Vit1
  • fbxo11
  • MGC84634
  • FBXO11
  • im:6906507
  • wu:fj83f06
  • zgc:153171
  • Fbxo11
  • DKFZp459P2410
  • F-box protein 11
  • F-box protein 11 L homeolog
  • F-box protein 11a
  • F-box only protein 11
  • hypothetical protein
  • FBXO11
  • Fbxo11
  • fbxo11.L
  • fbxo11a
  • CpipJ_CPIJ009919
  • CpipJ_CPIJ017549
  • Bm1_52225
  • LOAG_16571
  • fbxo11
  • LOC100115478
Epitop
Middle Region
12
10
8
5
5
4
4
4
3
3
3
3
3
1
1
1
Reaktivität
Hund, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus), Zebrafisch (Danio rerio)
80
27
26
4
4
4
3
3
3
3
3
2
2
1
1
1
Wirt
Kaninchen
59
21
Klonalität
Polyklonal
Konjugat
Unkonjugiert
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Applikation
Chromatin Immunoprecipitation (ChIP), Western Blotting (WB)
62
32
16
13
12
10
6
4
2
1
1
1
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen The immunogen is a synthetic peptide directed towards the middle region of human FBXO11
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN976727.
Sequenz HDVEFIRHDR FFCDCGAGTL SNPCTLAGEP THDTDTLYDS APPIESNTLQ
Homologie Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
Produktmerkmale This is a rabbit polyclonal antibody against FBXO11. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Andere Bezeichnung FBXO11 (FBXO11 Antibody Abstract)
Hintergrund FBXO11 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for FBXO11.This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.
Alias Symbols: FBX11, FLJ12673, MGC44383, PRMT9, UG063H01, VIT1, UBR6
Protein Interaction Partner: SKP1, ERN1, DTL, CUL1, EED, UBC, NEDD8, COPS5, COPS6, ELAVL1, USP16, HDAC6, BCL6, RBX1, TP53,
Protein Size: 843
Molekulargewicht 94 kDa
Gen-ID 80204
NCBI Accession NM_025133, NP_079409
UniProt Q6DF73
Pathways Sensory Perception of Sound
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 843 AA

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Bilder des Herstellers
Western Blotting (WB) image for anti-F-Box Protein 11 (FBXO11) (Middle Region) antibody (ABIN2774788) WB Suggested Anti-FBXO11 Antibody Titration: 0.2-1 ug/ml
ELISA Titer:
Chromatin Immunoprecipitation (ChIP) image for anti-F-Box Protein 11 (FBXO11) (Middle Region) antibody (ABIN2774788) Quiescent human colon carcinoma HCT116 cultures were treated with 10 % FBS for three ...
Allgemeine Veröffentlichungen Lee, Pal, Tasaki, Roy, Jiang, An, Banerjee, Kwon: "Synthetic heterovalent inhibitors targeting recognition E3 components of the N-end rule pathway." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 1, pp. 100-5, 2008 (PubMed).

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