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TRIM5 Antikörper

TRIM5 Reaktivität: Human, Maus WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7259897
  • Target Alle TRIM5 Antikörper anzeigen
    TRIM5 (Tripartite Motif Containing 5 (TRIM5))
    Reaktivität
    • 45
    • 4
    • 3
    • 1
    • 1
    Human, Maus
    Wirt
    • 39
    • 4
    • 2
    Kaninchen
    Klonalität
    • 40
    • 4
    Polyklonal
    Konjugat
    • 31
    • 4
    • 3
    • 3
    • 2
    • 2
    Dieser TRIM5 Antikörper ist unkonjugiert
    Applikation
    • 39
    • 28
    • 10
    • 10
    • 5
    • 4
    • 1
    • 1
    Western Blotting (WB)
    Produktmerkmale
    Polyclonal Antibody
    Aufreinigung
    Affinity purification
    Immunogen
    A synthetic peptide of human TRIM5 (NP_149083.2).
    Isotyp
    IgG
    Top Product
    Discover our top product TRIM5 Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    TRIM5 (Tripartite Motif Containing 5 (TRIM5))
    Andere Bezeichnung
    TRIM5 (TRIM5 Produkte)
    Synonyme
    TRIM5 antikoerper, RNF88 antikoerper, TRIM5alpha antikoerper, EG667823 antikoerper, Gm8833 antikoerper, RGD1304579 antikoerper, tripartite motif containing 5 antikoerper, tripartite motif-containing 5 antikoerper, TRIM5 antikoerper, Trim5 antikoerper
    Hintergrund
    The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein forms homo-oligomers via the coilel-coil region and localizes to cytoplasmic bodies. It appears to function as a E3 ubiquitin-ligase and ubiqutinates itself to regulate its subcellular localization. It may play a role in retroviral restriction. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
    Molekulargewicht

    Observed_MW: 50 kDa

    Calculated_MW: 29 kDa/31 kDa/37 kDa/40 kDa/46 kDa/56 kDa

    Gen-ID
    85363
    UniProt
    Q9C035
    Pathways
    Activation of Innate immune Response
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