TRIM5 Antikörper (C-Term)

Produktnummer ABIN655693

Produktdetails anti-TRIM5 Antikörper

Target: TRIM5 (Tripartite Motif Containing 5 (TRIM5))

Bindungsspezifität: AA 371-399, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRIM5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TRIM5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 371-399 amino acids from the C-terminal region of human TRIM5.

Klon: RB29688

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu TRIM5

Target: TRIM5 (Tripartite Motif Containing 5 (TRIM5))

Andere Bezeichnung: TRIM5 (TRIM5 Produkte)

Synonyme: TRIM5 antikoerper, RNF88 antikoerper, TRIM5alpha antikoerper, EG667823 antikoerper, Gm8833 antikoerper, RGD1304579 antikoerper, tripartite motif containing 5 antikoerper, tripartite motif-containing 5 antikoerper, TRIM5 antikoerper, Trim5 antikoerper

Hintergrund: The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein forms homo-oligomers via the coilel-coil region and localizes to cytoplasmic bodies. It appears to function as a E3 ubiquitin-ligase and ubiqutinates itself to regulate its subcellular localization. It may play a role in retroviral restriction. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Molekulargewicht: 56338

Gen-ID: 85363

NCBI Accession: NP_149023, NP_149083, NP_149084

UniProt: Q9C035

Pathways: Activation of Innate immune Response