PARP1 Antikörper (cleaved)

Produktnummer ABIN7005540

Produktdetails anti-PARP1 Antikörper

Target: PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))

Bindungsspezifität: cleaved

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PARP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktmerkmale: Monoclonal Antibody

Aufreinigung: Protein A purification

Immunogen: Synthetic Peptide

Klon: 4A3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.4.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PARP1

Target: PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))

Andere Bezeichnung: PARP1 (PARP1 Produkte)

Synonyme: ADPRT antikoerper, ADPRT 1 antikoerper, ADPRT1 antikoerper, ARTD1 antikoerper, PARP antikoerper, PARP-1 antikoerper, PPOL antikoerper, pADPRT-1 antikoerper, Adprt antikoerper, Parp-1 antikoerper, 5830444G22Rik antikoerper, AI893648 antikoerper, Adprp antikoerper, Adprt1 antikoerper, C80510 antikoerper, parp-1 antikoerper, sPARP-1 antikoerper, BEST:LD21673 antikoerper, CG17685 antikoerper, CG17696 antikoerper, CG17718 antikoerper, CG40411 antikoerper, D.PARP antikoerper, Dm.pARTa antikoerper, Dmel\\CG40411 antikoerper, LD21673.3prime antikoerper, PARP1 antikoerper, dPARP antikoerper, parp antikoerper, adprt1 antikoerper, padprt-1 antikoerper, ppol antikoerper, si:dkey-206f10.3 antikoerper, wu:fc60f12 antikoerper, zgc:110092 antikoerper, poly(ADP-ribose) polymerase 1 antikoerper, poly (ADP-ribose) polymerase 1 antikoerper, poly (ADP-ribose) polymerase family, member 1 antikoerper, Poly-(ADP-ribose) polymerase antikoerper, poly(ADP-ribose) polymerase 1 L homeolog antikoerper, PARP1 antikoerper, Parp1 antikoerper, Parp antikoerper, parp1.L antikoerper, parp1 antikoerper

Hintergrund: This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.

Molekulargewicht: 116,89 kDa

UniProt: P09874

Pathways: Apoptose, Caspase Kaskade in der Apoptose, DNA Reparatur, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location