SLC39A3 Antikörper (AA 110-160)

Produktnummer ABIN6991453

Produktdetails anti-SLC39A3 Antikörper

Target: SLC39A3 (Solute Carrier Family 39 (Zinc Transporter), Member 3 (SLC39A3))

Bindungsspezifität: AA 110-160

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC39A3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: ZIP3 Antibody is affinity chromatography purified via peptide column.

Immunogen: ZIP3 antibody was raised against a 16 amino acid synthetic peptide near the center of human ZIP3. The immunogen is located within amino acids 110 - 160 of ZIP3.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ZIP3 antibody can be used for detection of ZIP3 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL.

Antibody validated: Western Blot in mouse samples and Immunohistochemistry in mouse samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: ZIP3 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: ZIP3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu SLC39A3

Target: SLC39A3 (Solute Carrier Family 39 (Zinc Transporter), Member 3 (SLC39A3))

Andere Bezeichnung: ZIP3 (SLC39A3 Produkte)

Synonyme: AI845814 antikoerper, Zip3 antikoerper, ZIP3 antikoerper, wu:fc84e09 antikoerper, zgc:158334 antikoerper, solute carrier family 39 (zinc transporter), member 3 antikoerper, solute carrier family 39 member 3 antikoerper, Slc39a3 antikoerper, slc39a3 antikoerper, SLC39A3 antikoerper

Hintergrund: ZIP3 Antibody: The zinc transporter ZIP3, also known as SLC39A3, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. Similar to knock-outs of ZIP1 and ZIP2, ZIP3-null mice have no phenotypic differences compared to wild-type mice. Only when ZIP1, ZIP2, and ZIP3 genes are all eliminated and these mutant mice are fed a zinc-deficient diet do abnormalities such as reduced embryonic-membrane bound alkaline phosphatase activity and abnormal development occur, indicating that the ZIP1-3 proteins play an important, noncompensatory role when zinc is deficient. More recent studies have shown that ZIP2 and ZIP3 are down regulated in human prostate adenocarcinomatous glands, and may be important in the retention of zinc in the cellular compartment.

Gen-ID: 29985

NCBI Accession: NP_653165

UniProt: Q9BRY0

Pathways: NF-kappaB Signalweg, Neurotrophin Signalübertragung, Autophagie