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SLC39A3 Antikörper (Middle Region)

SLC39A3 Reaktivität: Human, Maus WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN955672
  • Target Alle SLC39A3 Antikörper anzeigen
    SLC39A3 (Solute Carrier Family 39 (Zinc Transporter), Member 3 (SLC39A3))
    Bindungsspezifität
    • 7
    • 6
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 113-142, Middle Region
    Reaktivität
    • 25
    • 11
    • 2
    Human, Maus
    Wirt
    • 25
    • 1
    Kaninchen
    Klonalität
    • 26
    Polyklonal
    Konjugat
    • 9
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SLC39A3 Antikörper ist unkonjugiert
    Applikation
    • 18
    • 15
    • 14
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Spezifität
    Recognizes SLC39A3 (Center).
    Aufreinigung
    Protein A column followed by peptide Affinity purification
    Immunogen
    KLH conjugated synthetic peptide between 113~142 amino acids from the Center region of Human SLC39A3 Genename: SLC39A3
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product SLC39A3 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) Sodium Azide as preservative
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    SLC39A3 (Solute Carrier Family 39 (Zinc Transporter), Member 3 (SLC39A3))
    Andere Bezeichnung
    Zinc Transporter ZIP3 / SLC39A3 (SLC39A3 Produkte)
    Synonyme
    AI845814 antikoerper, Zip3 antikoerper, ZIP3 antikoerper, wu:fc84e09 antikoerper, zgc:158334 antikoerper, solute carrier family 39 (zinc transporter), member 3 antikoerper, solute carrier family 39 member 3 antikoerper, Slc39a3 antikoerper, slc39a3 antikoerper, SLC39A3 antikoerper
    Hintergrund
    The zinc transporter ZIP3, also known as SLC39A3, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. Similar to knock-outs of ZIP1 and ZIP2, ZIP3-null mice have no phenotypic differences compared to wild-type mice. Only when ZIP1, ZIP2, and ZIP3 genes are all eliminated and these mutant mice are fed a zinc-deficient diet do abnormalities such as reduced embryonic-membrane bound alkaline phosphatase activity and abnormal development occur, indicating that the ZIP1-3 proteins play an important, noncompensatory role when zinc is deficient. More recent studies have shown that ZIP2 and ZIP3 are down regulated in human prostate adenocarcinomatous glands, and may be important in the retention of zinc in the cellular compartment.Synonyms: Solute carrier family 39 member 3, ZIP-3, ZIP3, Zrt- and Irt-like protein 3
    Gen-ID
    29985
    NCBI Accession
    NP_653165
    Pathways
    NF-kappaB Signalweg, Neurotrophin Signalübertragung, Autophagie
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